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TranscriptomicsTranscriptomic characterization of a virulence-deficient phosphatidylcholine-negative Agrobacterium tumefaciens mutant
To learn more about the global effects of phosphatidylcholine (PC)-deficiency in A. tumefaciens, we performed transcriptomic studies comparing the wild type and a PC-deficient DpmtA Dpcs mutant. We expanded the number of affected virulence genes and showed that the loss of PC was correlated with alt...
ORGANISM(S): Agrobacterium tumefaciens str. C58 
2010-04-07 | E-GEOD-21223 | biostudies-arrayexpress
TranscriptomicsAMPK epidermal inhibition promotes HuR cytoplasmic localization eliciting post-transcriptional inflammatory response in psoriasis
IL-20 cytokines are involved in the establishment of psoriasis, a common chronic skin inflammation epidemiologically associated with metabolic syndrome, but molecular mechanisms underlying their over-expression remain to be elucidated. We find that keratinocytes (KCs) expressed IL-20 and lymphocytes...
ORGANISM(S): Homo sapiens 
2015-09-08 | E-GEOD-50598 | biostudies-arrayexpress
ProteomicsIn-depth protein profiling of mouse hippocampal postsynaptic density using data-independent acquisition proteomics
In the present study, we catalogued the proteome of postsynaptic density (PSD) derived from the hippocampus of three-week old (P19) mice. samples in 100 min gradient time.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-08-27 | MSV000084240 | MassIVE
UnknownEvaluation of cognitive restructuring for post-traumatic stress disorder in people with severe mental illness.
Not available
S-EPMC4450219 | biostudies-literature
TranscriptomicsTranscription profiling of bovine early embryonic development in vivo using a bovine developmental array
Transcript abundance profiling analysis of bovine early embryonic development in vivo using a bovine developmental array.
ORGANISM(S): Bos taurus 
2009-06-01 | E-MEXP-2075 | biostudies-arrayexpress
ProteomicsDrosophila insulin-like peptides DILP2 and DILP5 stimulation global phosphoproteome
Insulin and IGF signaling (IIS) is a complex system that controls diverse processes including growth, development, metabolism, stress responses and aging. Drosophila melanogaster IIS is propagated by eight Drosophila insulin-like peptides (DILPs), homologues of both mammalian insulin and IGFs, with ...
ORGANISM(S): Drosophila melanogaster Drosophila melanogaster (Fruit fly) 
2018-10-19 | PXD009240 | Pride
Insulin-like peptide Insulin/igf signaling Dilp Drosophila 
ProteomicsMulti-omics data integration reveals correlated regulatory features of triple negative breast cancer
Triple negative breast cancer is an aggressive type of breast cancer with very little treatment options. TNBC is very heterogeneous with large alterations in the genomic, transcriptomic, and proteomic landscapes leading to various subtypes with differing responses to therapeutic treatments. We appli...
ORGANISM(S): Homo sapiens (Human) 
2021-06-24 | PXD025238 | Pride
Multi-omics data integration Phosphoproteomics Triple negative breast cancer Histone posttranslational modification Rna-seq 
Transcriptomicsaffy_ath_2012_04-Functional characterization of JMJ24, a putative histone demethylase
affy_ath_2012_04 - affy_ath_2012_04 - Epigenetic informations include histone post-translational modifications such as acetylation and methylation. The jumoni proteins can remove the methyl group from lysine or arginine residues of histones. The aim of this project is to compare gene expression leve...
ORGANISM(S): Arabidopsis thaliana 
2013-08-01 | E-GEOD-43728 | biostudies-arrayexpress
ProteomicsUbiquitination of the actin polymerase VASP
Filopodia are dynamic, actin-rich structures that extend outward from the cell to explore and respond to cues in the local environment. The actin polymerase VASP is a component of the filopodial tip complex, where it regulates actin polymerization and filopodial dynamics. Previously, we showed that ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-17 | PXD041196 | Pride
Actin  ubiquitin  vasp  post-translational modification 
ProteomicsTRIM9 and TRIM67 interactome using the BioID approach
TRIM9 and TRIM67 are two brain enriched E3 uiquitin ligases that are critical to neuronal form and function both during embryonic development and in adult-born neurons. TRIM9 and TRIM67 interact with cytoskeletal and exocytic proteins, but the full interactome is not known.Using the BioID approach w...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-04 | PXD021758 | Pride
Embryonic cortical neurons Orbitrap fusion lumos 
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