Post-acute sequelae of covid-19

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Univ. Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 – PLBS, F-59000 Lille, France (1)
Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US41 – UMS 2014 – PLBS, F-59000 Lille, France (1)

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Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. Modeling identified 4 PRO clusters based on reported deficit...

2024-01-12 | MTBLS850 | MetaboLights

Sequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often associated with debilitating symptoms and adverse multisystem consequences. We obtain plasma samples from 117 individuals during and 6 mth following their acute phase of infection to comprehensively profile and as...

2024-02-23 | MTBLS7337 | MetaboLights

Longitudinal multi-omics analysis of convalescent individuals with respiratory sequelae 6–36 months after COVID-19

This study presents a longitudinal multi-omics analysis of COVID-19 convalescents with respiratory sequelae, spanning 6–36 months post-infection. The integrating proteomic and metabolomic profiling uncovers persistent molecular alterations, impaired diffusing capacity for carbon monoxide, and propos...

ORGANISM(S): Homo Sapiens

2025-02-23 | PXD061113 |

Multiple Early Factors Anticipate Post-Acute COVID-19 Sequelae

Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However, quantifiable risk-factors for PASC and their biological associations are poorly resolved. We executed a deep multi-omic, longitudinal investigation of 309 COVID-19 patients from initial diagnosis to convalescence (2...

ORGANISM(S): Homo sapiens

2022-02-01 | E-MTAB-10129 | biostudies-arrayexpress

Immune signatures underlying post-acute COVID-19 lung sequelae

PRJNA735258 | ENA

Blood DNA methylation in post-acute sequelae of COVID-19 (PASC): a prospective cohort study

PRJNA1117967 | ENA

Blood DNA methylation in post-acute sequelae of COVID-19 (PASC): a prospective cohort study

PRJNA1117966 | ENA

Spatial Transcriptomics of the Epipharynx in Long COVID: Exploring SARS-CoV-2 Signalling Pathways and the Therapeutic Potential of Epipharyngeal Abrasive Therapy

10X VisiumHD spatial transcriptomics of epipharynx from three patients with long COVID and two control individuals without COVID-19.

ORGANISM(S): Homo sapiens

2025-02-24 | E-MTAB-14669 | biostudies-arrayexpress

Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae

PRJNA891054 | ENA

Immune signatures underlying post-acute COVID-19 lung sequelae

Although a substantial proportion of severe COVID-19 pneumonia survivors exhibit long-term pulmonary sequalae, the underlying mechanisms or associated local and systemic immune correlates are not known. Here, we have performed high dimensional characterization of the pathophysiological and immune tr...

ORGANISM(S): Homo sapiens

2021-09-17 | GSE176201 | GEO

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