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Menopause is associated with an increase in the prevalence and severity of hypertension in women. Although premenopausal females are protected against T cell-dependent immune activation and development of angiotensin II (Ang II) hypertension, this protection is lost in postmenopausal females. Theref...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD021233 | Pride
Estrogen dependent CD4+ T cell specific transcriptomic pathways identified in premenopausal protection against hypertension
Background: Premenopausal females are protected against T cell-dependent immune activation and development of angiotensin II (Ang II) hypertension compared to males and postmenopausal females. Therefore, the current study hypothesized that specific CD4+ T cell pathways are regulated by estrogen sign...
ORGANISM(S): Mus musculus 
2020-10-03 | GSE158946 | GEO
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