Postmortem brain tissue

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Unknown (862)
Transcriptomics (283)
Genomics (244)
Proteomics (72)
Methylation profiling (14)
Other (9)
Metabolomics (6)
Genomic (3)

Organisms

Homo sapiens (314)
Bombyx mori (53)
Schizosaccharomyces pombe (53)
Human immunodeficiency virus 1 (53)
Oryza sativa Indica Group (53)
Sinorhizobium meliloti BL225C (53)
Sus scrofa domesticus (53)
Ostreococcus tauri (53)
Saccharomyces cerevisiae (53)
Vitis vinifera (53)
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Pseudomonas aeruginosa SJTD-1 (53)
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Callithrix jacchus (2)
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Organisms

Homo sapiens (161)
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Repository

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geo (92)
pride (53)
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Tissue

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Brain (1)
Synapse (1)
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Pluripotent stem cell (1)
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Cerebral cortex (1)
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Disease

Alzheimer's disease (17)
Normal (6)
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Parkinson's disease (6)
Autism spectrum disorder (2)
Down syndrome (1)
Sporadic ALS (1)
Rett syndrome (1)
Advanced atherosclerosis (1)
Temporal lobe epilepsy (1)
Reference (1)
Acute promyelocytic leukemia (1)
Glioblastoma (1)
Breast cancer (1)
Alzheimer's disease 4 (1)
Substance-related disorder (1)
Multiple system atrophy (1)
Alzheimer's disease 3 (1)
Alzheimer's disease 1 (1)
FTDALS1 (1)
Lewy body dementia (1)
Amyotrophic lateral sclerosis (1)
Disease free (1)

Technology Type

Mass Spectrometry (53)
Shotgun proteomics (36)
Bottom-up proteomics (11)
Data-dependent acquisition (6)
Mass spectrometry (4)
HDMSE (3)
Data-independent acquisition (3)
Top-down proteomics (2)
Affinity purification coupled with mass spectrometry proteomics (2)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2000 (1)
Illumina HiSeq 2000, ILLUMINA (1)
Illumina Genome Analyzer II (1)
NMR spectroscopy (1)
Mass spectrometry assay (1)
Glycoproteomics (1)
SWATH MS (1)
Gel-based experiment (1)

Instrument Platform

Illumina HiSeq 2500 (6)
Agilent High resolution C scanner (4)
Illumina NovaSeq 6000 (4)
Illumina HiSeq 4000 (3)
NextSeq 500 (3)
Q Exactive (3)
Orbitrap Fusion Lumos (3)
BeadBug Benchtop homogenizer (2)
Affymetrix (2)
N/A (2)
Illumina HiSeq 2000 (2)
Orbitrap Exploris 480 (2)
Chromium Controller with Chromium Next GEM Single Cell 5’ and V(D)J (kits v1.1) (1)
Not applicable (1)
GenePix Personal 4100A [Axon Instruments] (1)
G2565AA DNA microarray scanner [Agilent] (1)
DNA Microarray Scanner BA [Agilent Technologies] (1)
Illumina Genome Analyzer II (1)
DNBSEQ-T7 (1)
Illumina MiSeq (1)
NextSeq 550 (1)
AB 5500xl Genetic Analyzer (1)
Q-Exactive HF (1)
MS:1000031 (1)
LTQ Orbitrap Velos (1)
TripleTOF 6600 (1)
Orbitrap Fusion (1)
Q Exactive HF (1)
TimsTOF Pro (1)
LTQ Orbitrap (1)

Publication Date

2010 (34)
2014 (33)
2015 (30)
2013 (29)
2026 (28)
2023 (28)
2025 (19)
2024 (19)
2021 (19)
2016 (19)
2012 (19)
2011 (19)
2008 (17)
2019 (14)
2022 (13)
2020 (13)
2018 (12)
2007 (12)
2017 (9)
2009 (9)
2006 (5)
2005 (5)
2004 (2)

UNIPROT ID/AC

Q9ULI1 (1)
O60636 (1)
O60312 (1)
Q9H244 (1)
Q9BZ76 (1)
Q8WUG5 (1)
Q5DX21 (1)
tr|N9V373|N9V373_MYCAR (1)
Q14833 (1)
Q96PZ7 (1)
Q14831 (1)
H7C3J4 (1)
P31644 (1)
Q9BYH1 (1)
P78333 (1)
O94779 (1)
P08908 (1)
Q93070 (1)
Q8TC71 (1)
Q9UQD0 (1)
Q9GZV7 (1)
Q96PE5 (1)
Q8WYK1 (1)
Q8N145 (1)
Q8IZS8 (1)
Q8IV01 (1)
Q86XE3 (1)
Q13875 (1)
Q09470 (1)
Q05586 (1)

ENSEMBL ID

ENSG00000229353 (1)
ENSG00000147251 (1)
ENSG00000170477 (1)

CHEBI ID

CHEBI:26271 (3)
CHEBI:26986 (3)
CHEBI:16811 (3)
CHEBI:25017 (3)
CHEBI:27266 (3)
CHEBI:46195 (3)
CHEBI:29016 (3)
CHEBI:16737 (3)
CHEBI:16919 (3)
CHEBI:27897 (3)
CHEBI:15354 (3)
CHEBI:17368 (3)
CHEBI:30769 (3)
CHEBI:177034 (2)
CHEBI:68428 (2)
CHEBI:75183 (2)
CHEBI:172431 (2)
CHEBI:37025 (2)
CHEBI:27618 (2)
CHEBI:16118 (2)
CHEBI:6377 (2)
CHEBI:23359 (2)
CHEBI:27399 (2)
CHEBI:8633 (2)
CHEBI:10043 (2)
CHEBI:17808 (2)
CHEBI:17043 (2)
CHEBI:47807 (2)
CHEBI:53678 (2)
CHEBI:17183 (2)

Metabolite Name

3-Chloro-L-tyrosine (2)
4-Chlorophenol (2)
L-(-)-Malic acid (2)
3-Hydroxy-3-methylglutaric acid (2)
N-Acetyl-DL-glutamic acid (2)
Myricetin (2)
Quercetin (2)
N4-Acetylsulfamethoxazole (2)
Oxazepam (2)
Folic acid (2)
Cysteine (2)
Rosuvastatin (2)
Ribitol (2)
Resveratrol (2)
Glutamate (2)
Leucine (2)
Esculin (2)
Aspartate (2)
4-Nitrophenol (2)
Valine (2)
Xanthohumol (2)
Dulcitol (2)
Estriol (2)
Trans-Cinnamic acid (2)
Succinic acid (2)
Dopamine (2)
L-Asparagine (2)
L-Ornithine (2)
Bisphenol A (2)
Methylmalonate (2)

First Public Date

2014 (40)
2025 (29)
2023 (22)
2026 (20)
2024 (20)
2021 (15)
2020 (14)
2022 (11)
2019 (9)
2017 (4)
2016 (4)
2018 (3)
2015 (3)
2013 (3)

Study type

Transcription profiling by array (144)
Methylation profiling by array (21)
RNA-seq of coding RNA (14)
Unknown experiment type (10)
Genotyping by array (5)
DNA-seq (5)
Comparative genomic hybridization by array (4)
Methylation profiling by high throughput sequencing (4)
RNA-seq of total RNA (4)
RNA-seq of non coding RNA (4)
Animal - One-color microarray (3)
RNA-seq of coding RNA from single cells (3)
ChIP-chip by tiling array (2)
Human - High-throughput sequencing (2)
Human - One-color microarray (2)
Other (2)
Transcription profiling by SAGE (1)
MicroRNA profiling by high-throughput sequencing (1)
Human - Methylation microarray (1)
Transcription profiling by RT-PCR (1)
Spatial transcriptomics by high-throughput sequencing (1)
ChIP-seq (1)
MicroRNA profiling by array (1)
Proteomic profiling by array (1)

Release Date

2023 (106)
2025 (103)
2024 (94)
2021 (90)
2022 (89)
2020 (79)
2014 (62)
2019 (54)
2018 (51)
2016 (50)
2015 (50)
2013 (42)
2010 (42)
2017 (36)
2011 (32)
2012 (30)
2008 (24)
2009 (18)
2026 (17)
2007 (13)
2006 (6)
2005 (5)
2004 (4)
2003 (1)
2001 (1)
1998 (1)

Lab affiliation

Vanderbilt University Department of Chemistry (3)
Lab of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, SP, Brazil (2)
University of Washington (2)
National Key Laboratory of Medical Molecular Biology and Department of Immunology; Institute of Basic Medical Sciences; Chinese Academy of Medical Sciences (1)
Biochemistry and Molecular Biophysics Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA Children's Hospital of Philadelphia Research Institute, Philadelphia, PA 19104, USA. (1)
Division of Neurobiology The Roslin Institute Royal (Dick) School of Veterinary Studies College of Medicine and Veterinary Medicine University of Edinburgh Easter Bush Midlothian EH25 9RG SCOTLAND, UK t: 44 (0)131 651 9119 e: T.M.Wishart@Roslin.ed.ac.uk website: http://www.roslin.ed.ac.uk/tom-wishart http://www.euanmacdonaldcentre.com/research.html (1)
Biochemistry and Molecular Biophysics Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA (1)
Biochemistry and Molecular Biophysics Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Children's Hospital of Philadelphia Research Institute, Philadelphia, PA 19104, USA. (1)
Children's Hospital of Philadelphia 416B Abramson Pediatric Research Center Philadelphia, PA 19104 Office: 215-590-5320 Lab: 215-590-5319 (1)
Bernstein Professor Emeritus in Adult Psychiatry Department of Psychiatry and Behavioral Sciences University of Minnesota Medical School Minneapolis, Minnesota, USA (1)
Laboratory of Molecular Neuro-oncology, The Rockefeller University, 1230 York Avenue, New York, NY 10065 (1)
Keck MS & Proteomics Resource MBB Department Yale University (1)
Lund University BME (1)
Neuroproteomics, Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Strasse 10, 13125 Berlin, Germany (1)
Departments of Biochemistry and Neurology Emory University School of Medicine (1)
Department of Biochemistry, Emory School of Medicine, Atlanta, Georgia, USA (1)
Department of immunology, Peking Union Medical College, Beijing, China (1)
Cognitive Disorder Research Unit, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden (1)
Department of Biomedical Sciences, Seoul National University College of Medicine 103 Daehakro Seoul 30380, Korea (1)
MIRCen, CNRS UMR 9199, Fontenay-aux-Roses, France (1)
Department of Molecular Medicine and Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA 92037, USA (1)
Laboratorio de Neuroinmunobiología, Departamento de Medicina Molecular y Bioprocesos. Instituto de Biotecnología, Universidad Nacional Autónoma de México (UNAM), Cuernavaca, Morelos 62210, México (1)
Department of Biomedical Engineering, Lund University, Lund, Sweden (1)
Biomedical Research Institute of Lleida Dr. Pifarré Foundation (IRBLLEIDA) - +Pec Proteomics Research Group (+PPRG) - Neuroscience Area – University Hospital Arnau de Vilanova (HUAV), 80 Av. Rovira Roure, 25198, Lleida, Spain Department of Medical Basic Sciences, University of Lleida (UdL), +Pec Proteomics Research Group (+PPRG), 25198, Lleida, Spain (1)
Lund University, Dept. Biomedical Engineering (1)
Department of Neurosciences, University of Toledo (1)
Department of Neuropathology, Medical Research institute and Center for Brain Integration Research, Tokyo Medical and Dental University (1)
Director of Women's Health Research Women's Service Line Inova Health System (1)
Faillace Department of Psychiatry and Behavioral Sciences University of Texas Health Science Center at Houston (1)
Structure Biology Department St Jude Children’s Research Hospital (1)

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Untargetted lipidomics dataset: LC-MS analysis in two postmortem brain areas of healthy individuals and schizophrenia patients.

Schizophrenia is a common mental illness. It is a complex disorder with many symptoms and cognitive impairments. Despite extensive study, the molecular mechanisms of this disease are still unknown. Present time studies on the lipid composition of the human brain are extremely fragmented. Of the p...

2024-06-04 | MTBLS8955 | MetaboLights

Genome-wide Expression Assay Comparison Across Frozen and Fixed Postmortem Brain Tissue Samples

Comparison between in vitro transcription- and cDNA-mediated annealing, selection and ligation (DASL)-based assays on brain-specific reference RNA, and postmortem frozen and formalin fixed brain tissue from autistic and control cases. Investigation of data preprocessing techniques for DASL-assayed ...

ORGANISM(S): Homo sapiens

2012-04-02 | E-GEOD-28475 | biostudies-arrayexpress

Transcription profiling of human adult postmortem brain tissue from Down syndrome and healthy control subjects

Down syndrome (DS) is the result of trisomy chromosome 21 but the mechanisms by which the genotype leads to the characteristic disease phenotype are unclear. We performed a microarray study using human adult brain tissue (dorsolateral prefrontal cortex) from DS subjects and healthy controls to chara...

ORGANISM(S): Homo sapiens

2009-04-23 | E-GEOD-5390 | biostudies-arrayexpress

DNA methylation in postmortem brain samples from autism cases and controls

We used the Illumina 450KMethylation BeadChip to measure DNA methylation at 485,512 loci across the genome for 40 postmortem brain samples. The purpose of our study was to identify differentially methylated regions (DMRs) associated with autism. Samples included 16 temporal cortex brain tissue sampl...

ORGANISM(S): Homo sapiens

2013-12-12 | E-GEOD-53162 | biostudies-arrayexpress

Transcription profiling of human adult postmortem brain tissue from subjects with bipolar disorder and healthy controls

This SuperSeries is composed of the following subset Series:; GSE5388: Adult postmortem brain tissue (dorsolateral prefrontal cortex) in subjects with bipolar disorder; GSE5389: Adult postmortem brain tissue (ortibtofrontal cortex) in subjects with bipolar disorder; Bipolar affective disorder is a s...

ORGANISM(S): Homo sapiens

2008-06-13 | E-GEOD-5392 | biostudies-arrayexpress

Proteomic profiling of postmortem prefrontal cortex tissue of suicide completers

A total of 36 postmortem brain samples (23 suicide completers, 13 control sudden death) were collected. We evaluated the proteome profile in the prefrontal cortex (Brodmann area 9, 10) with TMT-based quantification using LC-MS/MS. Several bioinformatics tools were used to elucidate biological mechan...

ORGANISM(S): Homo sapiens (Human)

2022-05-20 | PXD029845 | Pride

Framingham Heart Study RNA sequencing in postmortem brain tissue

PRJNA763280 | ENA

Bulk RNA-seq of postmortem human prefrontal cortex and cerebellum brain tissues

Analyzing brain region differences for postmortem Alzheimer's disease tissues.

ORGANISM(S): Homo sapiens

2024-06-30 | E-MTAB-14167 | biostudies-arrayexpress

Epigenome-wide association study of cocaine use disorder in postmortem human brain tissue

Analysis of cocaine use disorder (CUD) associated epigenome-wide DNA methylation (DNAm) alterations in human postmortem brain tissue of Brodmann Area 9. Tissue samples from N=21 CUD cases and N=21 individuals without CUD originating from the Douglas Bell Canada Brain Bank (DBCBB) were included. Epig...

EGAD00010002396 | EGA

Proteomics of 2 postmortem Human Brain Regions for Identification of Cognitive Resilience Factors

We implemented an integrative systems-level analysis of multi-region postmortem human brain proteomics derived from the Religious Order and Rush Memory and Aging Project (ROSMAP) to identify proteins and pathways significantly altered in resilient cases. ROSMAP is an information-rich longitudinal co...

ORGANISM(S): Homo sapiens (Human)

2023-07-20 | PXD040224 | Pride

Human brain Dlpfc Itc Proteome discoverer

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