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MetabolomicsClock regulation of metabolites reveals coupling between transcription and metabolism
The circadian clock is intricately connected with metabolism, however the precise details of these connections are incomplete. Here we used high temporal resolution metabolite profiling to determine circadian regulation of mouse liver and cell autonomous metabolism. In mouse liver, we found ~50% of ...
2017-04-05 | MTBLS292 | MetaboLights
ProteomicsThe leader peptide peTrpL forms antibiotic-containing ribonucleoprotein complexes for posttranscriptional regulation of multiresistance genes
Bacterial ribosome-dependent attenuators are widespread posttranscriptional regulators. They harbour small upstream ORFs (uORFs) encoding leader peptides, for which no functions in trans are known yet. In the soil-dwelling plant symbiont Sinorhizobium meliloti, the tryptophan biosynthesis gene trpE(...
ORGANISM(S): Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) 
2020-05-19 | PXD018342 | Pride
Small proteins Posttranscriptional regulation Attenuator Multiresistance Sinorhizobium meliloti Quantification 
ProteomicsReprograming of sRNA target specificity by the leader peptide peTrpL in response to antibiotic exposure
Trans-acting regulatory RNAs have the capacity to base pair with more mRNAs than experimentally detected under given conditions. This raises the question whether the sRNA target specificity can change upon metabolic or environmental changes. In Sinorhizobium meliloti, the sRNA rnTrpL is derived from...
ORGANISM(S): Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) 
2021-08-10 | PXD019516 | Pride
Small proteins Posttranscriptional regulation Attenuator Multiresistance Sinorhizobium meliloti Quantification 
UnknownPUM1 mediates the posttranscriptional regulation of human fetal hemoglobin.
Not available
S-EPMC9699939 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis roots - transcriptional and posttranscriptional regulation of transcription factor expression
Understanding how the expression of transcription factor (TF) genes is modulated is essential for reconstructing gene regulatory networks. There is increasing evidence that sequences other than upstream noncoding can contribute to modulating gene expression, but how frequently they do so remains unc...
ORGANISM(S): Arabidopsis thaliana 
2009-06-23 | E-GEOD-16468 | biostudies-arrayexpress
GenomicsRNA-binding protein A1CF modulates plasma triglyceride levels through posttranscriptional regulation of stress-induced VLDL secretion
RNA-binding protein A1CF modulates plasma triglyceride levels through posttranscriptional regulation of stress-induced VLDL secretion
PRJNA482762 | ENA
UnknownWidespread posttranscriptional regulation of cotransmission.
Not available
S-EPMC10413644 | biostudies-literature
TranscriptomicsCoordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response
Steady-state gene expression is a coordination of synthesis and decay of RNA through epigenetic regulation, transcription factors, miRNAs, and RNA-binding proteins. Here, we present Bru-Seq and BruChase-Seq to assess genome-wide changes to RNA synthesis and stability in human fibroblasts at homeosta...
ORGANISM(S): Homo sapiens 
2013-01-29 | E-GEOD-43440 | biostudies-arrayexpress
UnknownPosttranscriptional regulation of interleukin-10 expression by hsa-miR-106a.
Not available
S-EPMC2659714 | biostudies-literature
UnknownPosttranscriptional Regulation in Response to Different Environmental Stresses in Campylobacter jejuni.
Not available
S-EPMC9241687 | biostudies-literature
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