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GenomicsTranscription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells [EBF1]
Transcription factor Ebf1 is an important determinant of early B lymphopoiesis. To gain insight into differentiation stage-specific functions of Ebf1, we conditionally inactivated Ebf1. We found that Ebf1 is required for proliferation, survival and signaling of pro-B cells and peripheral B cell su...
ORGANISM(S): Mus musculus 
2012-04-02 | E-GEOD-35910 | biostudies-arrayexpress
GenomicsTranscription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells [H3K4me2 and H3K4me3]
Transcription factor Ebf1 is an important determinant of early B lymphopoiesis. To gain insight into differentiation stage-specific functions of Ebf1, we conditionally inactivated Ebf1. We found that Ebf1 is required for proliferation, survival and signaling of pro-B cells and peripheral B cell su...
ORGANISM(S): Mus musculus 
2012-04-02 | E-GEOD-35914 | biostudies-arrayexpress
GenomicsTranscription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells
This SuperSeries is composed of the following subset Series: GSE35910: Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells [EBF1] GSE35914: Transcription factor Ebf1 regulates differentiation stage-specific signaling, prolifer...
ORGANISM(S): Mus musculus 
2012-04-02 | E-GEOD-35915 | biostudies-arrayexpress
UnknownChronic alcohol abuse and spontaneous clearance of hepatitis C virus.
Not available
S-EPMC6667488 | biostudies-literature
GenomicsTranscriptional regulation by H3K122 acetylation in the lateral surface of the histone octamer
We characterize the acetylation of H3K122 for the first time. Towards this we mapped the genomic distribution of H3K122Ac, identified the enzyme introducing H3K122Ac, and addressed the functional contribution H3K122Ac to transcription. We found that H3K122Ac is associated with chromatin marks and ge...
ORGANISM(S): Homo sapiens 
2013-02-14 | E-GEOD-35954 | biostudies-arrayexpress
Unknown[Psychosocial crisis services-A special case of transsectoral healthcare].
Not available
S-EPMC12586391 | biostudies-literature
GenomicsGenome-wide mapping of EBF1 binding sites in murine pre B-cells
Early B cell factor-1 (Ebf1), a transcription factor expressed in B cells, adipocytes and neuronal cells, has been identified as a determinant in the specification of the B cell lineage in which Ebf1 acts in a regulatory network with the transcription factors E2A and Pax5. To gain insight into the ...
ORGANISM(S): Mus musculus 
2010-05-06 | E-GEOD-19971 | biostudies-arrayexpress
UnknownThe super-enhancer repertoire in porcine liver.
Not available
S-EPMC10024791 | biostudies-literature
UnknownNLRC4 expression in intestinal epithelial cells mediates protection against an enteric pathogen.
Not available
S-EPMC4020766 | biostudies-literature
TranscriptomicsTranslocations Activating IRF4 Identify a Subtype of Germinal-Center-Derived B-cell Lymphoma Affecting Predominantly Children and Young Adults
Background: Germinal center B-cell (GCB) lymphomas are common in children and adults. The prognosis strongly depends on age. Subgroups of GCB-lymphomas are characterized by chromosomal translocations affecting immunoglobulin (IG) loci leading to oncogene deregulation. Methods: Novel IG translocation...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-22470 | biostudies-arrayexpress
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