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TranscriptomicsCorrelating citric acid formation and manganese limitation in Aspergillus niger using transcriptome and proteome analysis
Aspergillus niger is well known for its capability to produce citrate in high amounts but the detailed metabolic response causing citrate production has not been fully elucidated. Manganese is known to have an important effect as its limitation is a requirement to obtain high-level citrate formation...
ORGANISM(S): Aspergillus niger 
2014-10-03 | E-GEOD-61985 | biostudies-arrayexpress
TranscriptomicsTranscription factor cooperativity in early adipogenic hotspots and super-enhancers
Here we have used a combination of advanced proteomics and genomics approaches to investigate the extent and mechanisms of transcription factor cross-talk at genomic hotspots. We identify ~12,000 transcription factor hotspots in the early phase of adipogenesis, and we find evidence of both simultane...
ORGANISM(S): Mus musculus 
2014-04-17 | E-GEOD-56872 | biostudies-arrayexpress
ProteomicsQuantitative Proteome Analysis Reveals Increased Content of Basement Membrane Proteins in Arteries from Patients with Type 2 Diabetes and Lower Levels among Metformin Users
We analyzed non-atherosclerotic repair arteries gathered at coronary by-pass operations from 30 patients with type 2 diabetes, as well as from 30 age- and gender-matched non-diabetic individuals. Quantitative proteome analysis was done by iTRAQ-labelling and LC-MS/MS analysis on individual arterial ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080848 | MassIVE
TranscriptomicsGene expression profiling in arterial tissue from type 2 diabetic patients
Gene expression profiling in arterial tissue from type 2 diabetic patients 10 patients with type 2 diabetes and 11 control subjects participated in the study
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-13760 | biostudies-arrayexpress
UnknownSARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate.
Not available
S-EPMC7532469 | biostudies-literature
UnknownA WAO - ARIA - GA²LEN consensus document on molecular-based allergy diagnostics.
Not available
S-EPMC3874689 | biostudies-literature
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