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Burkitt Lymphoma patient samples using gene expression to create a molecular definition of the disease. We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process. Keywords: clinical histo...
ORGANISM(S): Homo sapiens 
Activation of NFkB pathway by CARD11 Cy3-labelled untreated sample and Cy5-labelled treated sample were hybridized to a Lymphochip microarray.
ORGANISM(S): Homo sapiens 
To identify IRF4 transcription factor binding on chromatin at 5' regulatory regions of genes in myeloma cell line models. Keywords: binding site identification design Formaldehyde cross-linked, sonicated chromatin is prepared from cell lines Kms12 (test) and Ly19 (control). Chromatin immunoprecipate...
ORGANISM(S): Homo sapiens 
To identify c-myc target genes by siRNA transfection in a lymphoma cell line. Keywords: time series design OCI-Ly10 cells were transfected with c-myc siRNA pool versus control siRNA or buffer for a total of 4 microarrays.
ORGANISM(S): Homo sapiens 
Cancer cells display highly heterogeneous and plastic states in glioblastoma, an incurable brain tumour. However, how these malignant states arise and whether they follow defined cellular trajectories across tumours is poorly understood. Here, we generated a deep single cell and spatial multi-omic a...
ORGANISM(S): Homo sapiens 
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