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TranscriptomicsLow-power photodynamic therapy induces survival signaling in cultured hilar cholangiocarcinoma cells
Photodynamic therapy (PDT) of solid cancers comprises the administration of a photosensitizer followed by illumination of the photosensitizerreplete tumor with laser light. This induces a state of local oxidative stress, culminating in the destruction of tumor tissue and microvasculature and inducti...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-68292 | biostudies-arrayexpress
TranscriptomicsUnderstanding Vitamin D resistance using array comparative genomic hybridization
Vitamin D is the strongest known natural anti-proliferative. A large number of studies in a wide spectrum of cancers, including epidemiological, in vitro and animal models, demonstrate that the active form of Vitamin D has anti-cancer benefits, affecting both progression and metastasis. Alike the ro...
ORGANISM(S): Homo sapiens 
2008-05-31 | E-GEOD-9887 | biostudies-arrayexpress
TranscriptomicsBenzo[a]pyrene-induced changes in microRNA-mRNA networks
The microarray contains 9360 reporters, each present four times on the microarray. In our analysis 1326 human and viral reporters were used, of which 880 are unique human mature microRNAs. The other 8024 reporters represent microRNAs from other species. cDNA was generated using 1 M-NM-
ORGANISM(S): Homo sapiens 
2012-08-06 | E-GEOD-31252 | biostudies-arrayexpress
TranscriptomicsmiRNA profile of rat vascular smooth muscle cell stimulated by 2.6 mM high-phosphate
We compared time-series miRNA expression profile in high-phosphateM-bM-^@M-^Sstimulated rat vascular smooth muscle cells at 0, 3, and 12 hr respectively. Total RNA of rat VSMCs stimulated with 2.6 mM inorganic phosphate for 0, 3 or 12 hr was harvested by the Trizol method (Invitrogen) or use of the ...
ORGANISM(S): Rattus norvegicus 
2012-07-27 | E-GEOD-39700 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profiling in tumor-associated BMDCs induced by mouse ovarian and colon tumor cells
miRNA expression profiling in tumor-associated BMDCs induced by tumor cells 1D8 or CT-26 in comparison with those cultured in medium. To prepare tumor-associated BMDCs(Bone Marrow-derived Dendritic Cells), murine BMDCs were co-cultured with 1D8 or CT-26 cells in a transwell plate in 1640 medium supp...
ORGANISM(S): Mus musculus 
2012-12-05 | E-GEOD-42722 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression profiling during Adipocytic differentiation of human MSCs (hMSC-TERT)
We have employed whole microRNA microarray to identify changes in microRNA expression in human bone marrow MSCs (hMSC-TERT) during adipocytic differentiation in culture on day 7 and day 13 Human MSC line (hMSC-TERT) were subjectd to adipocytic differentiation for 7 days or 13 days, subsequently, RNA...
ORGANISM(S): Homo sapiens 
2014-09-09 | E-GEOD-59684 | biostudies-arrayexpress
TranscriptomicsPromiscuous RNA binding by PRC2
Polycomb repressive complex-2 (PRC2) is a histone methyltransferase required for epigenetic silencing during development and cancer. Long non-coding RNAs (lncRNAs) recruit PRC2 to chromatin, but the general role of RNA in maintaining repressed chromatin is unknown. ChIP-seq, combined with RNA-seq, i...
ORGANISM(S): Homo sapiens 
2013-09-28 | E-GEOD-50177 | biostudies-arrayexpress
TranscriptomicsmiRNA in mouse macrophages
By employing miRCURY LNAM-bM-^DM-" microRNA Array, we have identified a subset of 21 top miRNAs that are differentially expressed between GM-BMM and M-BMM cells To know the differential expression of miRNA in mouse GM-CSF-induced bone marrow-derived macrophages (GM-BMM) vs. M-CSF-induced BMM (M-BMM)
ORGANISM(S): Mus musculus 
2013-04-17 | E-GEOD-46085 | biostudies-arrayexpress
TranscriptomicsEffect of ultradian light-dark cycles on the transcriptome of mice carying a human Per3 polymorphism
In humans, a primate-specific variable-number tandem-repeat (VNTR) polymorphism (4 or 5 repeats 54 nt in length) in the circadian gene PER3 is associated with differences in sleep timing and homeostatic responses to sleep loss. We investigated the effects of this polymorphism on circadian rhythmicit...
ORGANISM(S): Mus musculus 
2014-03-11 | E-GEOD-55495 | biostudies-arrayexpress
TranscriptomicsBinding in wild type, D and SoxN mutant embryos: SoxN vs D.
Genome-wide binding of transcription factors SoxN and D in stage 12-17 wild type embryos (SoxNDam and DDam), of SoxN in D mutants (D-SoxNDam) and of D in SoxN mutants (SoxN-DDam). Four DamID experiments. Three biological replicates per experiment. Two conditions: Dam (control) vs SoxNDam or DDam or ...
ORGANISM(S): Drosophila melanogaster 
2014-04-23 | E-GEOD-47228 | biostudies-arrayexpress
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