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GenomicsInternational Multiple Sclerosis Genomics Consortium (IMSGC) Genome Wide Association Study of Multiple Sclerosis

The goal of this study is to perform a comprehensive allelic and genotypic association analysis of the entire human genome in multiple sclerosis. The recent definitive linkage genome screen demonstrated that there is no other MS risk gene with an effect size anywhere near that of the MHC. How...

phs000139.v1.p1 | EGA
GenomicsDeregulation of the Ras-Erk Signaling Axis Modulates the Enhancer Landscape [ChIP-seq]
Unrestrained receptor tyrosine kinase (RTK) signaling and epigenetic deregulation are root causes of tumorigenesis. We establish linkage between these processes by demonstrating that aberrant RTK signaling unleashed by oncogenic HRasG12V or loss of negative feedback through Sprouty gene deletion rem...
ORGANISM(S): Mus musculus 
2015-08-22 | E-GEOD-64190 | biostudies-arrayexpress
TranscriptomicsCandidate prostate cancer genes through comparative expression-profiling of seminal vesicle
BACKGROUND: Prostate cancer is the most frequently diagnosed cancer among men in the United States. In contrast, cancer of the seminal vesicle is exceedingly rare, despite that the prostate and seminal vesicle share similar histology, secretory function, androgen dependency, blood supply, and (in p...
ORGANISM(S): Homo sapiens 
2008-05-08 | E-GEOD-11376 | biostudies-arrayexpress
TranscriptomicsArray CGH data of 64 prostate cancer specimens
The dataset comprises array CGH data of 64 prostate cancer specimens performed on Stanford cDNA microarrays, to accompany the study of J Lapointe et al (2007). For each array, Channel 2 represents Cy5-labeled prostate genomic DNA, and Channel 1 Cy3-labeled normal male genomic DNA. Set of arrays org...
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-6469 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of breast cancer cell lines defines relevant tumor models
This SuperSeries is composed of the following subset Series: GSE13914: Molecular profiling of breast cancer cell lines defines relevant tumor models (aCGH) GSE15361: Molecular profiling of breast cancer cell lines defines relevant tumor models (gene expression) Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-15376 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of breast cancer cell lines defines relevant tumor models (aCGH)
Breast cancer cell lines have been used widely to investigate breast cancer pathobiology and new therapies. Breast cancer is a molecularly heterogeneous disease, and it is important to understand how well and which cell lines best model that diversity. In particular, microarray studies have identi...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-13914 | biostudies-arrayexpress
GenomicsATD
WTCCC1 project Autoimmune Thyroid Disease (ATD) samples
EGAD00000000011 | EGA
GenomicsWTCCC case-control study for Autoimmune Thyroid Disease - Combined Controls
WTCCC genome-wide case-control association study for Autoimmune Thyroid Disease (ATD) - Combined Controls.
EGAS00000000021 | EGA
GenomicsWTCCC case-control study for Autoimmune Thyroid Disease
WTCCC genome-wide case-control association study for Autoimmune Thyroid Disease (ATD) using the 1958 British Birth Cohort collection as controls.
EGAS00000000020 | EGA
GenomicsBC
WTCCC1 project Breast cancer (BC) samples
EGAD00000000013 | EGA
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