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Affinity enrichment of ligand to mutant and wild-type PP2A protein
ORGANISM(S): Homo sapiens (Human) 
2020-06-09 | PXD010709 | Pride
MicroRNAs (miRNAs) have emerged as novel cancer genes. In particular, the 17~92 cluster of miRNAs is highly expressed in haematopoietic cancers and promotes lymphomagenesis in vivo1,2. Clinical use of these findings hinges on isolating the oncogenic activity within the 17~92 cluster and defining its...
ORGANISM(S): Mus musculus 
Epigenetic changes largely contribute to the regulation of gene expression in cancer cells. DNA methylation is part of the epigenetic gene regulation complex which is relevant for the pathogenesis of cancer. We performed a genome-wide search for methylated CpG islands in tumors and corresponding non...
ORGANISM(S): Homo sapiens 
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