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TranscriptomicsRNA-seq of human oesophageal adenocarcinoma OE19 cell line following PPARGC1A knock-down and 24 hour lapatinib treatment
To determine genes regulated by the transcriptional co-activator PPARGC1A in OAC cells and whether PPARGC1A activity is altered by lapatinib we performed RNA-seq on OE19 cells treated with non-targeting siRNA or siRNA targeting PPARGC1A. 24 hours post-transfection, cells were also treated with eithe...
ORGANISM(S): Homo sapiens 
2022-09-26 | E-MTAB-10317 | biostudies-arrayexpress
GenomicsGenome-wide maps of the total and lysine methylated enriched pools of peroxisome proliferating activated receptor gamma (pparg) co-activator 1 alpha (ppargc1a) in Hepa 1-6 cells
We report the application of single nucleotide sequencing technology for high-throughput profiling of ppargc1a in mouse hepatome cells (Hepa1-6). By obtaining 1.2 billion bases of sequence from chromatin immunoprecipitated DNA, we generated genome-wide maps of ppargc1a sin mouse hepatoma cells. We ...
ORGANISM(S): Mus musculus 
2017-05-01 | E-GEOD-57852 | biostudies-arrayexpress
GenomicsmRNA expression profiling A549 lung cancer cells following PPARGC1A suppression
mRNA expression profiling A549 lung cancer cells following PPARGC1A suppression
PRJNA659234 | ENA
GenomicsImpact of knocking out Ppargc1a in intestinal stem cells on mucosal homeostasis
Impact of knocking out Ppargc1a in intestinal stem cells on mucosal homeostasis
PRJNA778403 | ENA
GenomicsChIP-seq of PPARGC1A in oesophageal adenocarcinoma OE19 cells treated with lapatinib
ChIP-seq of PPARGC1A in oesophageal adenocarcinoma OE19 cells treated with lapatinib
PRJEB49950 | ENA
TranscriptomicsmRNA expression profiling A549 lung cancer cells following PPARGC1A suppression
PPARGC1A oppositely regulates cancer metastasis in melanoma, breast, and pancreatic cancer; however, little is known about its impact on lung cancer metastasis. We generated gene-expression profile of control and PPARGC1A suppressed A549 cells, a lung adenocarcinoma cell line that expresses moderate...
ORGANISM(S): Homo sapiens 
2021-08-16 | GSE156833 | GEO
TranscriptomicsEffect of Ppargc1a overexpression in mouse heart
Ppargc1a overexpression in heart tissue measured using RNA sequencing
ORGANISM(S): Mus musculus 
2017-09-08 | GSE77795 | GEO
TranscriptomicsImpact of knocking out Ppargc1a in intestinal stem cells on mucosal homeostasis
We report the application of single cell RNAseq assay in examining the effect of Ppargc1a gene expression in intestinal stem cells on mucosal homeostasis. Lgr5EGFPcreERT2 mice were crossed with Ppargc1a F/+ or F/F to selectively target gene expression in Lgr5 expressing intestinal stem cells. Mice w...
ORGANISM(S): Mus musculus 
2023-04-12 | GSE188339 | GEO
GenomicsRNA-seq of human oesophageal adenocarcinoma OE19 cell line following PPARGC1A knock-down and 24 hour lapatinib treatment
RNA-seq of human oesophageal adenocarcinoma OE19 cell line following PPARGC1A knock-down and 24 hour lapatinib treatment
PRJEB44104 | ENA
GenomicsChIP-seq of HNF4A, PPARGC1A and H3K27ac in oesophageal adenocarcinoma OE19 cells treated with lapatinib
ChIP-seq of HNF4A, PPARGC1A and H3K27ac in oesophageal adenocarcinoma OE19 cells treated with lapatinib
PRJEB44106 | ENA
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