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TranscriptomicsAnalysis of Ppif-/- hearts
To identify differences in gene expression between peptidylprolyl isomerase F (cyclophilin D; Ppif)-null hearts and WT control hearts. RNA was isolated from mice 8 weeks of age to discover gene changes prior to myocardial dysfunction. Three replicates each of Ppif-/- and WT mice.
ORGANISM(S): Mus musculus 
2011-01-05 | E-GEOD-23028 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of PPIF knockdown in human dermal fibroblasts and keratinocytes
To determine the effect of CyD knockdown through gapmer-mediated knockdown of PPIF gene in pathogenic functions related to wound healing
ORGANISM(S): Homo sapiens 
2024-04-01 | E-MTAB-13920 | biostudies-arrayexpress
TranscriptomicsAnalysis of Ppif-/- hearts
To identify differences in gene expression between peptidylprolyl isomerase F (cyclophilin D; Ppif)-null hearts and WT control hearts.
ORGANISM(S): Mus musculus 
2011-01-05 | GSE23028 | GEO
GenomicsMus musculus
Analysis of Ppif-/- hearts
PRJNA131849 | ENA
TranscriptomicsCyclophilin D extramitochondrial signaling controls cell cycle progression and chemokine-directed cell motility.
Mitochondria control bioenergetics and cell fate decisions, but whether they also participate in extra-organelle signaling is not understood. Here, we show that interference with cyclophilin D (CypD), a mitochondrial matrix protein and apoptosis regulator, causes accelerated cell proliferation and ...
ORGANISM(S): Mus musculus 
2013-03-08 | E-GEOD-41280 | biostudies-arrayexpress
UnknownUnveiling the role of PPIF and macrophage subtypes in LSCC progression via single-cell and exosome RNA sequencing.
Not available
S-EPMC11933383 | biostudies-literature
UnknownOverexpression of TICRR and PPIF confer poor prognosis in endometrial cancer identified by gene co-expression network analysis.
Not available
S-EPMC7906164 | biostudies-literature
GenomicsNynrin preserves hematopoietic stem cell function by inhibiting the mitochondrial permeability transition pore opening (ChIP_Seq)
Mitochondria have recently been identified as a critical regulator for the homeostasis of hematopoietic stem cells (HSCs). However, the mechanism underlying HSC regulation still needs to be clarified. Here, we identify transcription factor Nynrin as a novel regulator of HSC maintenance through modul...
ORGANISM(S): Mus musculus 
2024-06-01 | GSE248635 | GEO
TranscriptomicsNynrin preserves hematopoietic stem cell function by inhibiting the mitochondrial permeability transition pore opening (RNA-Seq for Nynrin cko HSC)
Mitochondria have recently been identified as a critical regulator for the homeostasis of hematopoietic stem cells (HSCs). However, the mechanism underlying HSC regulation still needs to be clarified. Here, we identify transcription factor Nynrin as a novel regulator of HSC maintenance through modul...
ORGANISM(S): Mus musculus 
2024-06-01 | GSE248637 | GEO
TranscriptomicsNynrin preserves hematopoietic stem cell function by inhibiting the mitochondrial permeability transition pore opening （human_HSC_RNA_Seq)
Mitochondria have recently been identified as a critical regulator for the homeostasis of hematopoietic stem cells (HSCs). However, the mechanism underlying HSC regulation still needs to be clarified. Here, we identify transcription factor Nynrin as a novel regulator of HSC maintenance through modul...
ORGANISM(S): Homo sapiens 
2024-06-01 | GSE248636 | GEO
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