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ORGANISM(S): Xenopus tropicalis 
Our previous studies have shown that inhibition of the IGF-1R pathway by the IGF-1RTK inhibitor picropodophyllin (PPP) can be achieved and also constitutes a favorable therapeutic window in multiple myeloma (MM). As no complete remission using in vivo models of MM could be obtained, a combinatorial ...
ORGANISM(S): Homo sapiens 
Lactiplantibacillus plantarum strain:ppp Genome sequencing
Lactiplantibacillus plantarum strain:ppp Genome sequencing
Total, polysome and monosome RNAseq of Caenorhabditis elegans strains ppp-1(wrm10), ppp-1(wrm15) and wild type
Tendon is a hypocellular tissue that contains functional cable-like units of type I collagen responsible for the transmission of force from muscle to bone. In the setting of injury or disease, patients can develop chronic tendinopathies that are characterized by pain, loss of function and persistent...
ORGANISM(S): Rattus norvegicus 
In this study, the distribution and regulation of periplasmic and cytoplasmic carbon fluxes in Gluconobacter oxydans 621H with glucose were studied by 13C-based metabolic flux analysis (13C-MFA) in combination with transcriptomics and enzyme assays. For 13C-MFA, cells were cultivated with specifical...
ORGANISM(S): Gluconobacter oxydans 621H 
We compared the ratio of polysome-associated mRNAs (>3 ribosomes/mRNA) normalized to total mRNA levels between WT and ppp-1 animals. We found a significant de-enrichment of 336 mRNAs and an enrichment for 72 mRNAs in ppp-1 polysome fractions.
ORGANISM(S): Caenorhabditis elegans 
2020-02-01 | GSE144607 | GEO
We have developed a chemical proteomic strategy for the systematic interrogation of endogenous phosphoprotein phosphatases (PPP) and their interacting proteins, including regulatory and scaffolding subunits, and substrates (the 'PPPome'). PPPs are captured using an immobilized non-selective PPP inhi...
ORGANISM(S): Neurospora Crassa (ncbitaxon:5141) Candida Albicans (ncbitaxon:5476) Saccharomyces Cerevisiae (ncbitaxon:4932) Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) Schizosaccharomyces Pombe (ncbitaxon:4896) 
2017-07-07 | MSV000081226 | MassIVE
Circulating extracellular vesicles (cEV) are released by many kinds of cells and play an important role in cellular communication, signaling, inflammation modulation, coagulation and tumor growth. cEV are of growing interest, not only as biomarkers, but also as potential treatment targets. However, ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-06 | PXD033117 | Pride
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