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ProteomicsConstruction and analysis of the testis/sperm-enriched interaction network: identification of potential PPP1CC2 complexes as targets for male contraception
Phosphoprotein phosphatase 1 catalytic subunit gamma 2 (PPP1CC2), a PPP1 isoform restricted to testicular germ cells and spermatozoa, is essential for completion of spermatogenesis and highly similar PPP1C isoforms are capable of compensating for the loss of Ppp1cc in every tissue except in testis. ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-28 | PXD002888 | Pride
Human Sperm Ppp1cc2 
UnknownSignificant expression levels of transgenic PPP1CC2 in testis and sperm are required to overcome the male infertility phenotype of Ppp1cc null mice.
Not available
S-EPMC3474748 | biostudies-literature
UnknownExpression of transgenic PPP1CC2 in the testis of Ppp1cc-null mice rescues spermatid viability and spermiation but does not restore normal sperm tail ultrastructure, sperm motility, or fertility.
Not available
S-EPMC2849817 | biostudies-literature
UnknownTCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network.
Not available
S-EPMC3654263 | biostudies-literature
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