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ProteomicsPQBP1-associated proteins spectrums in HEK-293 cells
Our study shows that deletion of the alternative splicing regulator PQBP1 in striatal progenitors resulted in defective striatal development due to impaired neurogenesis of spiny projection neurons (SPNs). Therefore, we further reveal that PQBP1 associated with components in splicing machinery by LC...
ORGANISM(S): Homo sapiens (Human) 
2023-03-16 | PXD040439 | Pride
Pqbp1  hek-293 cells  lc-msms 
TranscriptomicsNext-generation sequencing identifies mRNAs targets that experience significant changes in alternative splicing upon PQBP1 knockdown in mouse embryonic cortical neurons
PQBP1 is a highly conserved protein closely related to neurodegenerative disorders. We identified PQBP1 as an important alternative splicing effector necessary for maintaining normal neuron functions in the brain. In order to explore PQBP1's functions in alternative splicing regulation and neuronal ...
ORGANISM(S): Mus musculus 
2013-03-15 | E-GEOD-44402 | biostudies-arrayexpress
ProteomicsPCK2-mediated PQBP1 lactylation promotes asthmatic inflammation through PRMT5 inhibition
Background: Asthma involves chronic inflammation linked to metabolic reprogramming, but how metabolites reshape epigenetics through post-translational modifications remains unclear. Methods: We used HDM-induced asthmatic mice with multi-omics analyses (metabolomics, PTM-proteomics, ChIP-seq) and val...
ORGANISM(S): Homo Sapiens 
2025-11-12 | PXD070618 |
GenomicshNSCs siRNA BRPF1, DYRK1A et PQBP1
hNSCs siRNA BRPF1, DYRK1A et PQBP1
PRJNA1040232 | ENA
GenomicsRNA immunoprecipitation sequencing (RIP-seq) of PQBP1 in ovarian cancer cells
RNA immunoprecipitation sequencing (RIP-seq) of PQBP1 in ovarian cancer cells
PRJNA924814 | ENA
GenomicsSpyTag-based CLIP (SpyCLIP) sequencing of PQBP1 in ovarian cancer cells
SpyTag-based CLIP (SpyCLIP) sequencing of PQBP1 in ovarian cancer cells
PRJNA925204 | ENA
GenomicsRNA sequencing (RNA-seq) of PQBP1 knockdown in ovarian cancer cells
RNA sequencing (RNA-seq) of PQBP1 knockdown in ovarian cancer cells
PRJNA924813 | ENA
GenomicsPQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation
PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation
PRJNA935784 | ENA
GenomicsLong-read nanopore sequencing (Nanopore-seq) of PQBP1 knockdown in ovarian cancer cells
Long-read nanopore sequencing (Nanopore-seq) of PQBP1 knockdown in ovarian cancer cells
PRJNA924816 | ENA
TranscriptomicsRNA sequencing (RNA-seq) of PQBP1 knockdown in ovarian cancer cells
To investigate the comprehensive function of PQBP1 in the regulation of RNA splicing, we established Dox-inducible PQBP1 knockdown HEY cell line. We then performed gene expression profiling analysis using data obtained from RNA-seq of PQBP1 knockdown and control HEY cells (three biological replicati...
ORGANISM(S): Homo sapiens 
2024-05-01 | GSE223091 | GEO
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