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TranscriptomicsSingle-cell RNA and B cell receptor profiling of B cell response to SARS-CoV-2 vaccination
We generated single-cell transcriptomic and BCR sequencing data of B cells from peripheral blood samples taken from a SARS-CoV-2-antigen-naive cohort being vaccinated with the SARS-CoV-2 mRNA-1273 vaccine. Blood samples were collected at the baseline timepoint D-1 (i.e. one day prior to the initial ...
ORGANISM(S): Homo sapiens 
2026-05-08 | E-MTAB-16531 | biostudies-arrayexpress
TranscriptomicsGermline Aberrations of PAX5 Cause Susceptibility to pre-B cell Acute Lymphoblastic Leukemia
A novel heterozygous germline variant, c.547G>A (p.Gly183Ser), in the paired box protein encoding gene, PAX5, was found to segregate with disease in two unrelated kindreds with autosomal dominant pre-B cell acute lymphoblastic leukemia (ALL). Leukemic cells from both families exhibited 9p deletion, ...
ORGANISM(S): Mus musculus 
2014-04-06 | E-GEOD-45834 | biostudies-arrayexpress
UnknownCediranib for metastatic alveolar soft part sarcoma.
Not available
S-EPMC3677840 | biostudies-literature
Transcriptomics16S rRNA sequencing of cecal microbiota from neonatal mice pre- and post-weaning
Neonatal mice were susceptible to cryptosporidium infection at 1- and 2-weeks of age, but were resistant to infection at 3- and 6-weeks of age. Diet and microbial changes are known to occur during the weaning transition in mice and we hypothesized that these changes in the intestinal luminal environ...
ORGANISM(S): mouse gut metagenome 
2020-11-03 | E-MTAB-9100 | biostudies-arrayexpress
GenomicsWTCCC3_Pre-Eclampsia
WTCCC3 UK maternal cases of pre-eclampsia
EGAD00010000854 | EGA
GenomicsRUNX1 reshapes the epigenetic landscape at the onset of hematopoiesis
Cell fate decisions during hematopoiesis are governed by lineage-specific transcription factors, such as RUNX1, SCL/TAL1, FLI1 and C/EBP family members. In order to gain insight about how these transcription factors regulate the activation of hematopoietic genes during embryonic development, we meas...
ORGANISM(S): Mus musculus 
2012-10-18 | E-GEOD-40235 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human pheochromocytomas of various genetic origins
Pheochromocytomas are neural crest-derived tumors that arise from inherited or sporadic mutations in at least six independent genes: RET, VHL, NF1, and subunits B, C and D of succinate dehydrogenase (SDH). The proteins encoded by these multiple genes regulate distinct functions. To identify molecula...
ORGANISM(S): Homo sapiens 
2007-06-21 | E-GEOD-2841 | biostudies-arrayexpress
TranscriptomicsRUNX1 reshapes the epigenetic landscape at the onset of hematopoiesis
Cell fate decisions during hematopoiesis are governed by lineage-specific transcription factors, such as RUNX1, SCL/TAL1, FLI1 and C/EBP family members. In order to gain insight about how these transcription factors regulate the activation of hematopoietic genes during embryonic development, we meas...
ORGANISM(S): Mus musculus 
2013-02-11 | E-GEOD-39662 | biostudies-arrayexpress
TranscriptomicsLactobacillus johnsonii NCC comparative genomics with L. iatae
Whole genome DNA microarray designed for the probiotic L. johnsonii strain NCC533 was used for comparative genomic hybridization (CGH) of L. johnsonii ATCC 33200T, L. johnsonii BL261, L. gasseri ATCC 33323T and L. iatae BL263 (CECT 7394T). In these experiments, the fluorescence ratio distributions o...
ORGANISM(S): Lactobacillus johnsonii 
2010-11-24 | E-GEOD-21627 | biostudies-arrayexpress
TranscriptomicsBifidobacterium longum mutants and resistance to Heat-Shock
Transcriptional profiling of Bifidobacterium longum mutants versus wt strain in exponentional phase, with or without heat-shock treatment, and in stationary phase Keywords: Characterization of natural mutants Two B. longum mutants (NCC2912 and NCC2913) were analysed versus the wt strain NCC2705 in ...
ORGANISM(S): Bifidobacterium longum 
2010-05-17 | E-GEOD-14628 | biostudies-arrayexpress
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