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TranscriptomicsRNA-seq of micro RNAs (miRNAs) in Human prefrontal cortex to identify differentially expressed miRNAs between Huntington's Disease and control brain samples
To identify genome-wide differentially expressed microRNAs (miRNAs) between Huntington's disease (HD) and control Human pre-frontal cortex samples
ORGANISM(S): Homo sapiens 
2014-01-30 | E-MTAB-2206 | biostudies-arrayexpress
ProteomicsCharacterization of human aging and Parkinson’s disease pre-frontal cortex by multi-omics: a glycomics, proteomics study.
This study identifies the age and PD related changes in glycans (HS and CS disaccharides) and proteomics in human aging and Parkinson’s disease. We analyzed the prefrontal cortex for changes in HS, CS and proteomic signatures in young versus aged as well as aged and PD in two cohorts. These studies ...
ORGANISM(S): Homo sapiens (Human) 
2020-07-16 | PXD018736 | Pride
Chondroitin sulfate Mass spectrometry Reverse phase Hilic-wax Multi-omics Label-free proteomics Pre-frontal cortex Heparan sulfate Lc-msms. Proteomic Parkinson’s disease Glycomic Aging 
ProteomicsWdr13-/0 compared to wild-type mice hippocampus and pre-frontal cortex iTRAQ proteomics
Wdr13 has been implicated in memory and mental disorders, particularly in X-linked intellectual disability (XLID) in animal studies and in humans. The exact molecular function of Wdr13 is still largely unknown. In order to find out the role of Wdr13 in brain, we chose to characterize Wdr13 gene knoc...
ORGANISM(S): Mus musculus (Mouse) 
2017-01-03 | PXD002466 | Pride
Hippocampus Pre-frontal cortex Mice Itraq Wdr13-/0 
TranscriptomicsTranscription profiling by array of human normal pre-frontal cortex, liver, and colon tissues and colon tumors
DNA methylation, at CpG islands and promoters, is often inversely correlated with gene expression. We used expression microarrays to determine the relationship between DNA methylation and gene expression in 5 normal prefrontal cortex samples and 5 normal liver samples from the same individuals as we...
ORGANISM(S): Homo sapiens 
2009-01-23 | E-GEOD-13471 | biostudies-arrayexpress
ProteomicsInter-regional proteomic profiling of the human brain using optimized protein extraction method from formalin-fixed tissue to identify signaling pathways
Proteomics offers vast potential to study the molecular regulation of the human brain. Formalin fixation is a common method for preserving human tissue, however, presents challenges for proteomic analysis. In this study we compared the efficiency of two different protein extraction buffers on three ...
ORGANISM(S): Homo sapiens (Human) 
2023-02-22 | PXD039808 | Pride
Formalin-fixed Proteomics Brain Mass spectrometry Pathways Protein Region Method Human Signaling 
TranscriptomicsRNA-Seq of Pre-frontal cortex (PFC) and Amygdala from 3-6 month old adult mice
We sequenced RNA from Pre-frontal cortex (PFC) and Amygdala from 3-6 month old adult mice.
ORGANISM(S): Mus musculus 
2016-01-27 | GSE74630 | GEO
TranscriptomicsQuantification of gene expression from primate tissue samples
We have quantified gene expression in five tissues (brain, heart, kidney, liver and testis) from humans, chimpanzees and rhesus macaques using the Illumina NlaIII Digital Gene Expression (DGE) protocol. This dataset extends a previous microarray study by Khaitovich et al. (Khaitovich et al. 2005) wi...
ORGANISM(S): Pan troglodytes 
2013-10-01 | E-GEOD-50782 | biostudies-arrayexpress
GenomicsMus musculus
RNA-Seq of Pre-frontal cortex (PFC) and Amygdala from 3-6 month old adult mice
PRJNA301035 | ENA
TranscriptomicsRNA-seq of prefrontal cortex in adult human, chimp and macaque
The human brain has changed dramatically since humans diverged from our closest living relatives, chimpanzees and the other great apes. However, the genetic and developmental programs underlying this divergence are not fully understood. Here, we generate single-nucleus RNA-seq data of human, chimpan...
ORGANISM(S): Homo sapiens 
2019-10-04 | E-MTAB-8231 | biostudies-arrayexpress
UnknownHypohydration alters pre-frontal cortex haemodynamics, but does not impair motor learning.
Not available
S-EPMC9458583 | biostudies-literature
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