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TranscriptomicsRNA-Seq of Pre-frontal cortex (PFC) and Amygdala from 3-6 month old adult mice
We sequenced RNA from Pre-frontal cortex (PFC) and Amygdala from 3-6 month old adult mice.
ORGANISM(S): Mus musculus 
2016-01-27 | GSE74630 | GEO
TranscriptomicsFyn-dependent prefrontal cortex gene networks in acute ethanol sensitivity
Fyn kinase has been implicated in multiple behavioral responses to ethanol and in the regulation of myelin gene expression. Here we tested whether Fyn kinase modulated basal or ethanol-responsive expression of genes regulated by acute ethanol in brain regions of the mesolimbocortical dopamine pathwa...
ORGANISM(S): Mus musculus 
2014-08-31 | E-GEOD-49028 | biostudies-arrayexpress
GenomicsMus musculus
RNA-Seq of Pre-frontal cortex (PFC) and Amygdala from 3-6 month old adult mice
PRJNA301035 | ENA
TranscriptomicsExpression data from naM-CM-/ve and MPTP-exposed cholinergic transgenic mice
PD is the second most common neurodegenerative disease worldwide with growing prevalence. MPTP is a neurotoxin which causes the appearance of Parkinson's disease (PD) pathology. The involvement of the cholinergic system in PD has been identified decades ago and anti-cholinergic drugs were upon the...
ORGANISM(S): Mus musculus 
2012-01-09 | E-GEOD-31458 | biostudies-arrayexpress
ProteomicsProteomic analysis of a rat streptozotocin model shows dysregulated biological pathways implicated in Alzheimer’s Disease
Alzheimer’s Disease (AD) is an age-related neurodegenerative disorder characterized by progres-sive memory loss and cognitive impairment, affecting 35 million individuals worldwide. Intracer-ebroventricular (ICV) injection of low to moderate doses of STZ in adult male Wistar rats can re-produce clas...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-06-22 | PXD048720 | Pride
Pre-frontal cortex (pfc)  hippocampus (hpc)  streptozotocin 
UnknownHypohydration alters pre-frontal cortex haemodynamics, but does not impair motor learning.
Not available
S-EPMC9458583 | biostudies-literature
TranscriptomicsMicroarray profiling of PFC, HPC and STR from subjects with schizophrenia, bipolar, MDD or control
Schizophrenia is a complex psychiatric disorder encompassing a range of symptoms and etiology dependent upon the interaction of genetic and environmental factors. Several risk genes, such as DISC1, have been associated with schizophrenia as well as bipolar disorder (BPD) and major depressive disor...
ORGANISM(S): Homo sapiens 
2014-01-11 | E-GEOD-53987 | biostudies-arrayexpress
TranscriptomicsCross-tissue methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer’s disease neuropathology
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder that is characterized by progressive neuropathology and cognitive decline. We performed a cross-tissue analysis of methylomic variation in AD using samples from three independent human post-mortem brain cohorts. We identified a differe...
ORGANISM(S): Homo sapiens 
2014-08-17 | E-GEOD-59685 | biostudies-arrayexpress
UnknownThe role of the frontal cortex in memory: an investigation of the Von Restorff effect.
Not available
S-EPMC4073090 | biostudies-literature
UnknownLesions in different prefrontal sectors are associated with different types of acquired personality disturbances.
Not available
S-EPMC8816872 | biostudies-literature
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