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Genomics (1109)
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Tissue

Cell culture (51)
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Diabetes, non-alcoholic lipid liver disease / non-alcoholicity fat hepatitis, inflammatory bowel disease (ulcerative colitis, Crohn’s disease), irritable bowel disease, neuroimmune disease, lung cancer, esophageal cancer, gastric cancer, colorectal cancer (1)
Sarcoma (1)
Hereditary Breast and Ovarian Cancer Syndrome (1)
Pancreatic Neoplasms (1)
Metastatic colorectal cancer (1)
Neoplasm Metastasis (1)
Carcinoma (1)
Rectal Neoplasms (1)

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Mass Spectrometry (264)
Shotgun proteomics (109)
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Mass spectrometry (34)
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Data-dependent acquisition (28)
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Mass spectrometry assay (12)
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HiSeq X Ten (ILLUMINA), HiSeq X Ten, ILLUMINA (1)
ILLUMINA, NextSeq 500, HiSeq X Ten (1)
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ABI_SOLID, Illumina HiSeq 2000, Illumina 450K, AB 5500xl Genetic Analyzer, AB 5500 Genetic Analyzer, ILLUMINA (1)
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Instrument Platform

Illumina NovaSeq 6000 (17)
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NextSeq 500 (4)
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TripleTOF 6600 (2)
High-performance computing workstation (1)
Protocol computer workstation running R statistical software (1)
Thermal cycler (PCR); Covaris ME220 focused ultrasonicator; magnetic separation rack; Agilent TapeStation system (D5000 and D1000 ScreenTape assays); Qubit fluorometer or equivalent; microcentrifuge. (1)
JANUS® G3 MDT automated liquid handling workstation (PerkinElmer); thermal cycler or incubator (42 °C); Zymo DNA Clean & Concentrator columns; AMPure XP magnetic bead purification system; magnetic separation rack. (1)
Multichannel pipettes or automated liquid handler; 384-well tissue culture plates; Class II biological safety cabinet; CO₂ incubator (37 °C, 5% CO₂). (1)
TruSeq RNA Sample Preparation protocol (1)
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NA (1)
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Orbitrap Exploris 240 (1)

Publication Date

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2019 (37)
2018 (26)
2017 (18)
2014 (12)
2016 (10)
2015 (10)
2013 (6)
2010 (4)
2012 (3)
2007 (2)

CHEBI ID

CHEBI:15428 (16)
CHEBI:30769 (16)
CHEBI:24898 (14)
CHEBI:28044 (14)
CHEBI:27266 (14)
CHEBI:18237 (14)
CHEBI:16919 (14)
CHEBI:18186 (13)
CHEBI:28300 (13)
CHEBI:25017 (13)
CHEBI:25094 (13)
CHEBI:16449 (13)
CHEBI:16737 (13)
CHEBI:27897 (13)
CHEBI:26271 (12)
CHEBI:26986 (12)
CHEBI:6650 (12)
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CHEBI:17822 (11)
CHEBI:22660 (11)
CHEBI:27570 (11)
CHEBI:16811 (11)
CHEBI:17234 (11)
CHEBI:30746 (11)
CHEBI:18211 (11)
CHEBI:16359 (11)
CHEBI:17568 (11)
CHEBI:32816 (11)
CHEBI:30915 (11)

Metabolite Name

Creatine (10)
Creatinine (9)
Urea (8)
Glycine (8)
Trimethylamine N-oxide (7)
N-acetylputrescine (7)
N-acetylglycine (7)
Methionine sulfoxide (7)
Deoxycarnitine (7)
1-methylhistidine (7)
Dimethylglycine (7)
Tryptophan (7)
Taurine (7)
Serine (7)
Lysine (7)
Glutamate (7)
Cysteine (7)
Cystathionine (7)
Citrulline (7)
Betaine (7)
Arginine (7)
Allantoin (7)
Adenine (7)
Phenylalanine (7)
Tyrosine (7)
Threonine (7)
Glucose (7)
Choline (7)
Creatine (7)
Glutamine (7)

First Public Date

2025 (165)
2026 (157)
2024 (137)
2022 (105)
2023 (95)
2021 (80)
2020 (55)
2019 (48)
2018 (31)
2014 (28)
2015 (21)
2017 (19)
2016 (8)
2013 (5)

Modelling Approach

Constraint-based model (2)
Machine learning (1)
Mathematical model (1)
Boolean model (1)
Population model (1)
Ordinary differential equation model (1)

Study status

Recruiting (6)
Not provided (3)
Not yet recruiting (1)
Completed (1)

Lab affiliation

Markus Ralser, Prof. Dr. Einstein Professor of Biochemistry Head, Institute of Biochemistry, Charité University Medicine, Berlin markus.ralser@charite.de Senior Group Leader, The Francis Crick Institute, London markus.ralser@crick.ac.uk (3)
Penn State College of Medicine, Department of Medicine, Penn State Cancer Institute. (3)
State Key Laboratory of Proteomics, National Center for Protein Sciences Beijing, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing 102206, China (3)
Virginia Tech, Biological Sciences (3)
Department of Convergence Medicine, Convergence Medicine Research Center/Biomedical Research Center, Asan Medical Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea. (2)
Dept. Proteomics and Signal Transduction Director at the Max-Planck Institute of Biochemistry (2)
Director, Research Unit for Precision Regenerative Medicine, Helmholtz Munich Professor, Systems Biology of Airways and Lungs, Ludwig-Maximilians University (LMU) Munich Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research (DZL) (2)
Director, Translational Proteomics Research Unit, IRCM Director, Biomarker Pipeline for Precision Medicine Strategic Initiative Full IRCM Research Professor Full Research Professor, Department of Biochemistry and Molecular Medicine (accreditation for the Molecular Biology Programs), Université de Montréal Holder of the Bell-Bombardier Chair of Excellence Person in charge of responsible conduct of research, IRCM (2)
Division of Nephrology, University Hospitals Namur | Place Louise Godin 15, B-5000 Namur, Belgium (2)
General Manager of PROMEC Department of Clinical and Molecular Medicine +4773598508 +4772573342 Laboratoriesenteret, 231.04.008, Øya, Erling Skjalgssons gate 1 Norway (2)
Helmholtz Munich (2)
Institute of Advanced Clinical Medicine, Institute of Medical Technology, Peking University Beijing, China. (2)
Lee Kong Chian School of Medicine, School of Biological Sciences, Nanyang Technological University, Singapore (2)
Max Planck Institute for Infection Biology, Berlin, Germany (2)
NHMRC Senior Research Fellow Department of Biochemistry and Molecular Biology | Faculty of Medicine, Dentistry and Health Sciences Level 2 South, Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road The University of Melbourne, Victoria 3010 Australia (2)
School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, and Precision Medicine Research Program, Hunter Medical Research Institute, NSW, 2308, Australia (2)
University of Cincinnati Department of Pathology and Laboratory Medicine (2)
1 Affiliated Hangzhou First People’s Hospital, State Key Laboratory of Medical Proteomics, School of Medicine, School of Future Biomedicine, Westlake University, Hangzhou, Zhejiang Province, China. 2 Westlake Center for Intelligent Proteomics, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang Province, China. 3 Research Center for Industries of the Future, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province, China. (1)
1 Precision Medicine Programme, Yong Loo Lin School of Medicine (YLLSoM), National University of Singapore, 2 NUS Centre for Cancer Research, National University of Singapore, 3 Department of Biochemistry, YLLSoM, National University of Singapore (1)
1)VIB Center for Medical Biotechnology, Technologiepark-Zwijnaarde 75, B9052 Ghent, Belgium 2)Department of Biomolecular Medicine, Ghent University, Technologiepark-Zwijnaarde 75, B9052 Ghent, Belgium 3)VIB Proteomics Core, Technologiepark-Zwijnaarde 75, B9052 Ghent, Belgium (1)
1. Cancer Signalling Research Group, School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, NSW, AUSTRALIA 2. Precision Medicine Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, AUSTRALIA 3. Paediatric Program, Mark Hughes Foundation Centre for Brain Cancer Research, College of Health, Medicine, and Wellbeing, Callaghan, NSW, AUSTRALIA (1)
1. Monash Proteomics and Metabolomics Facility, Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia 2. School of Clinical Sciences, Department of Medicine, Monash University, Clayton, Victoria, Australia (1)
1. Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark; 2. Proteomics and Singal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany (1)
1. Precision Medicine Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. 2. Cardiovascular Disease Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. 3. Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. (1)
1. Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Department of Neurology, Fuzhou 350108, China 2.School of Medicine, The Chinese University of Hong Kong, Shenzhen 518172, China (1)
1.Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China (1)
1Academy of Orthopedics, Guangdong Province, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China 2The Third School of Clinical Medicine, Southern Medical University, Guangzhou, China (1)
1School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, University of Newcastle, NSW, 2308, Australia 2 Precision Medicine Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, 2305, Australia (1)
2. Wellcome MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK (1)
Aalborg university (1)

Keyword

BRCA testing (1)
Return of genetic research results (1)
EHealth (1)
Digital health (1)
Risk communication (1)
ELSI (1)

IsPrivate

False (7)

Submitter Keywords

Machine Learning Model (1)
Manuscript Accepted (1)
COVID-19 (1)

Classification

bacteria (3)
protozoa (2)

Modification

4-tetrahydrothiazine-3-carboxylic acid (2)
2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (20)
RNA-seq of coding RNA (17)
Observational (6)
RNA-seq of non coding RNA (4)
Interventional (4)
Unknown experiment type (2)
ChIP-seq (2)
DNA-seq (2)
Methylation profiling by array (2)
RNA-seq of non coding RNA from single cells (1)
Human - Two-color microarray (1)
One-color microarray (1)
Human - High-throughput sequencing (1)
Human - One-color microarray (1)
Animal - High-throughput sequencing (1)
Bisulfite-seq (1)
Comparative genomic hybridization by array (1)
ATAC-seq (1)
Other (1)
ScATAC-seq (1)
RNA-seq of coding RNA from single cells (1)
RNA-seq of total RNA (1)
Observational patient registry (1)

Release Date

2025 (6567)
2023 (4582)
2024 (4564)
2022 (4553)
2021 (3691)
2020 (2588)
2019 (1792)
2018 (1251)
2026 (1032)
2017 (878)
2016 (617)
2015 (316)
2014 (204)
2013 (88)
2012 (68)
2011 (42)
2010 (37)
2009 (22)
2008 (22)
2007 (18)
2005 (10)
2006 (7)
2003 (7)
2000 (4)
2004 (3)
2001 (3)

Location

Japan (2)
China (2)
United States (2)
Finland (1)
Italy (1)
Canada (1)

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Digital Phenomics and Dual-Fluid Metabolomics for Precision Stratification of Diabetic Kidney Disease: A Multicenter Cohort Study

We conducted a prospective-retrospective two-center cohort study involving 364 participants. The Discovery Cohort (n=282) enrolled from two centers consisted of healthy controls (n=80), patients with type 2 diabetes mellitus (T2DM) without kidney disease (n=102), and patients with confirmed DKD (...

2026-03-09 | MTBLS14007 | MetaboLights

Using a rhabdomyosarcoma patient-derived xenograft to examine precision medicine approaches and model acquired resistance.

Original patient tumor is directly implanted in mice xenografts. Tumor is propagated to multiple mice for conduct of 6 arm treatment trials and control. Therapies are selected based on T0 and F0 genomic profiles. ICE-T refractory tumor are implanted and additional 6 arm treatment trial and control c...

ORGANISM(S): Homo sapiens

2014-07-22 | E-GEOD-51130 | biostudies-arrayexpress

The Brazilian Initiative on Precision Medicine (BIPMed)

PRJNA658602 | ENA

Ovarian Cancer Precision Medicine Initiative (OCPMI)

PRJNA1456165 | ENA

Ovarian Cancer Precision Medicine Initiative (OCPMI)

PRJNA1456164 | ENA

Precision medicine for ABCA4 disease: modifier alleles

PRJNA717338 | ENA

Precision medicine for ABCA4 disease: modifier alleles

PRJNA717339 | ENA

The Brazilian Initiative on Precision Medicine (BIPMed)

The development of precision medicine strategies requires prior knowledge of the genetic background of the target population. However, despite the availability of data from admixed Americans within large reference population databases, we cannot use these data as a surrogate for that of the Brazilia...

ORGANISM(S): Homo Sapiens

2020-07-07 | PRJEB39251 | EVA

Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity

In the present study we created and analyzed cardiomyocytes from two separate iPSC clones from the fibroblasts of five different female individuals and two male individuals, using footprint-free Sendai virus RNA-seq of iPSC cardiomyocytes, Ampli-seq of heart left ventricle and iPSC cardiomyocytes (w...

ORGANISM(S): Homo sapiens

2016-08-24 | E-GEOD-83668 | biostudies-arrayexpress

Proteomic analysis of single tears from healthy human subjects

23 volunteers were recruited for this study. Tears were collected using microcapillary tubes (MCT). For each volunteer, a single tear sample was taken from one eye. For two of these volunteers, the procedure was performed in the morning (9-10 AM) and in the afternoon (5-6 PM) on the same day, once a...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2021-06-25 | MSV000087703 | MassIVE