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MetabolomicsMultiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health

In order to explore opportunities for personalized and predictive health care, we collected serial clinical measurements, health surveys and multiomics profiles (genomics, proteomics, autoantibodies, metabolomics and gut microbiome) from 96 individuals. The participants underwent data-driven heal...

2021-09-02 | MTBLS2187 | MetaboLights
MetabolomicsData processing, multi-omic pathway mapping, and metabolite activity analysis using XCMS Online

Systems biology is the study of complex living organisms, and as such, analysis on a systems-wide scale involves the collection of information-dense data sets that are representative of an entire phenotype. To uncover dynamic biological mechanisms, bioinformatics tools have become essential to fa...

2017-11-23 | MTBLS572 | MetaboLights
GenomicsLinking molecular responses to organismal outcomes under complex contaminant stress: a systems biology approach for predictive ecotoxicology
Linking molecular responses to organismal outcomes under complex contaminant stress: a systems biology approach for predictive ecotoxicology
PRJNA1456480 | ENA
TranscriptomicsStructural systems biology evaluation of metabolic thermotolerance in Escherichia coli
Investigation of whole genome gene expression level in E. coli K-12 MG1655 in glucose M9 minimal media with/without heatshock A six chip study using total RNA recovered from E. coli K-12 MG1655 grown up to OD600nm 0.6 (mid-exponential phase) in M9 minimal media supplemented with 0.2% glucose with/wi...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2013-06-20 | E-GEOD-42675 | biostudies-arrayexpress
UnknownTurning high-throughput structural biology into predictive inhibitor design.
Not available
S-EPMC10089178 | biostudies-literature
UnknownIdentifying cryptic diversity with predictive phylogeography.
Not available
S-EPMC5095379 | biostudies-literature
TranscriptomicsNetwork Biology of Tumor Stem-like Cells Identified a Regulatory Role of CBX5 in Lung Cancer
Mounting evidence points to a link between a cancer possessing stem-like properties and a worse prognosis. To understand the biology, a common approach is to integrate network biology with signal processing mechanics. That said, even with the right tools, predicting the risk for a highly susceptible...
ORGANISM(S): Homo sapiens 
2012-08-17 | E-GEOD-35603 | biostudies-arrayexpress
TranscriptomicsA possible role of miRNAs as predictive markers for the recurrence of hepatocellular carcinoma after liver transplantation
Background and aims: Liver transplantation (LT) is the most radical treatment for hepatocellular carcinoma (HCC) with high rates of long-term survival, but tumor recurrence after LT is an unresolved problem. The aim of our study was to identify predictive markers for tumor recurrence after liver tra...
ORGANISM(S): Homo sapiens 
2016-03-01 | E-GEOD-64989 | biostudies-arrayexpress
GenomicsChemical Systems Biology Reveals Mechanisms of Dissociated Glucocorticoid Receptor Signaling
Chemical Systems Biology Reveals Mechanisms of Dissociated Glucocorticoid Receptor Signaling
PRJNA628707 | ENA
TranscriptomicsLinking molecular responses to organismal outcomes under complex contaminant stress: a systems biology approach for predictive ecotoxicology
Ecological risk assessments have traditionally relied on simplified models that expose single species to individual chemicals under controlled laboratory conditions. However, real-world ecosystems are subject to multiple, interacting stressors, particularly from anthropogenic sources, that challenge...
ORGANISM(S): Daphnia magna 
2026-07-01 | GSE328764 | GEO
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