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MetabolomicsAnalysis of fecal microbiome and metabolome changes in goats with pregnant toxemia

Pregnancy toxemia is a common disease, which occurs in older ewes that are pregnant with multiple lambs in the third trimester. Most of the sick goats die within a few days, which can seriously impact the economic benefits of goat breeding enterprises. The disease is believed to be caused by maln...

2024-10-01 | MTBLS7519 | MetaboLights
MetabolomicsMetabolomics highlights reduced glutamate and acetylcarnitine in the amniotic fluid of cytomegalovirus-infected pregnant women

Cytomegalovirus (CMV) is a ubiquitous infectious agent that causes significant morbidity in immunosuppressed hosts and is the most common cause of neonatal congenital deafness.An infection acquired during pregnancy can be vertically transmitted to the fetus and cause permanent sequelae in the new...

2025-09-12 | MTBLS12415 | MetaboLights
MetabolomicsLACTIN-V (Lactobacillus crispatus CTV-05) leads to microbial and immune modulation in pregnant women at risk of spontaneous preterm birth: FLIP-1 study

Preterm birth (PTB) remains a leading cause of neonatal morbidity and mortality, with no new preventive therapeutics introduced since the 1970s. Evidence increasingly implicates adverse vaginal microbiome-immune interactions in its aetiology. We report the effects of the live biotherapeutic, Lact...

2026-10-02 | MTBLS15899 | MetaboLights
MetabolomicsUrine metabolic profiles of pregnant women in relation to environmental exposures
Not available
ORGANISM(S): Homo sapiens 
ST000855 | MetabolomicsWorkbench
TranscriptomicsTranscriptome profile form endometrial biopsy samples of pregnant and non-pregnant cows
Purpose: characterize the uterine transcriptome profiles of pregnant (P) versus non-pregnant (NP) cows during early pregnancy and attempted to define a potential set of marker genes that can be valuable for predicting pregnancy outcome. Methods: beef cows were synchronized and artificially inseminat...
ORGANISM(S): Bos indicus 
2015-04-09 | E-GEOD-65117 | biostudies-arrayexpress
MetabolomicsEffects of Zika virus infection on the metabolome of pregnant women: a longitudinal study
Not available
ORGANISM(S): Homo sapiens 
ST002048 | MetabolomicsWorkbench
TranscriptomicsGene Expression Profiles of Pregnant and Non-pregnant Whole Blood
Comparison of gene expression profiles in whole blood collected from pregnant and non-pregnant females. Peripheral whole blood samples from 5 third trimester pregnant females and 5 non-pregnant females were collected. The gene expression profiles of the two groups were compared using Affymetrix HG-U...
ORGANISM(S): Homo sapiens 
2009-06-10 | E-GEOD-14771 | biostudies-arrayexpress
TranscriptomicsLow dose hCG pregnant vs non-pregnant
Influence of ovarian stimulation with 200 IU of hCG, (administered in the late follicular phase among ICSI patients undergoing a GnRH-antagonist protocol), on the endometrium on the day of oocyte pick-up. The purpose of the present study is to assess the influence of the administration of low dose h...
ORGANISM(S): Homo sapiens 
2010-09-07 | E-GEOD-21225 | biostudies-arrayexpress
MetabolomicsExposures to Metals in Pregnant Women and the Impact on Fetal Development and Birth Outcomes in Suriname
Not available
ORGANISM(S): Homo sapiens 
ST002118 | MetabolomicsWorkbench
TranscriptomicsRNA-seq of pancreatic islets from pregnant mice
During pregnancy, the energy requirements of the fetus impose changes in maternal metabolism. Increasing insulin resistance in the mother maintains nutrient flow to the growing fetus, while prolactin and placental lactogen counterbalance this resistance and prevent maternal hyperglycemia by driving ...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-21860 | biostudies-arrayexpress
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