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Posttraumatic stress disorder (PTSD) is a prevalent psychiatric disorder. Several studies have attempted to characterize molecular alterations associated with PTSD, but most findings were limited to the investigation of specific cellular markers in the periphery or defined brain regions. In the curr...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-17 | PXD002272 | Pride
Comparative RNA-Seq in mouse prelimbic cortex (PL)
The medial prefrontal cortex (mPFC) is a key brain region involved in controlling working memory, executive function, and self-regulatory behaviours, and its malfunction is a hallmark of several neuropsychiatric disorders such as schizophrenia, depression, and post-traumatic stress disorder. One of ...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD047291 | Pride
Analysis of miRNA Changes in the prelimbic cortex of Rat with Chronic Neuropathic Pain
Analysis of mRNA Changes in the prelimbic cortex of Rat with Chronic Neuropathic Pain
Histone deacetylase 5 in prelimbic prefrontal cortex limits context-associated cocaine-seeking behavior
Distinct transcriptomic profiles in the dorsal hippocampus and prelimbic cortex are transiently regulated following episodic learning
Time dependent coordinated hippocampal-prefrontal cortical interactions are required for the long-term storage of memories. However, the role of prefrontal cortex (PFC) in encoding of long-term memories remains elusive. Here, we discover a critical role of PFC in the encoding of contextual memories ...
ORGANISM(S): Mus musculus 
2017-01-06 | GSE61529 | GEO
Molecular profiling of prelimbic projections to NAc, BLA, and VTA using vTRAP
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