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TranscriptomicsmicroRNA-Seq of Gallus gallus embryo tissues: Undetermined Presomitic Mesoderm (PSM), Determined PSM, and Limb bud
This analysis aims at finding the microRNAs present in three chick embryo undifferentiated tissues (pools of tissues): Undetermined Presomitic Mesoderm (PSM-U), Determined Presomitic Mesoderm (PSM-D) and Distal limb bud (Limb).
ORGANISM(S): Gallus gallus 
2021-10-25 | E-MTAB-8176 | biostudies-arrayexpress
TranscriptomicsMurine E9.5 embryo PSM and newly formed somites: Paraxis-/- vs WT
Transcriptional profiling of E9.5 mouse embryo tissue from the presomitic mesoderm (PSM) and somites I-IV. Tissue from embryos lacking a functional Paraxis gene (Paraxis-/-) was compared to identical tissue from E9.5 Wild Type embryos. The goal was to identify genes that had become deregulated in th...
ORGANISM(S): Mus musculus 
2013-12-05 | E-GEOD-47905 | biostudies-arrayexpress
ProteomicsSubcellular proteomics of murine presomitic mesoderm
We studied the effects of different stimuli on on the subcellular proteome of primary murine presomitic mesoderm tissue (PSM) in two separate experiments. In the first experiment, tissue was treated ex vivo with either fructose-6-phosphate, fructose-1,6-bisphosphate, or control treatment before subc...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-07 | PXD029988 | Pride
Fructose-1 Subcellular proteomics Tmt Presomitic mesoderm 6-bisphosphate Fructose-6-phosphate Glycolysis Subcellular fractionation Lc-ms/ms 
TranscriptomicsRNAseq of mouse presomitic mesoderm segments along the anteroposterior embryo axis.
Somitogenesis is the segmentation of the developing embryonic body axis into somites and is guided by oscillating genes, which create waves of expression that travel across the presomitic mesoderm (PSM) from posterior to anterior. Upon arrival of a wave at the PSM's anterior end, a new somite is for...
ORGANISM(S): Mus musculus 
2017-12-01 | E-MTAB-6155 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of murine presomitic mesoderms of 17 samples at various time points to identify cyclic genes of the mouse segmentation clock
A microarray time series was generated to identify cyclic genes of the segmentation clock in the mouse. The right posterior half presomitic mesoderms (PSM) from 17 mouse embryos were dissected while the contralateral side of the embryo containing the left PSM was immediately fixed to be analyzed by ...
ORGANISM(S): Mus musculus 
2006-11-06 | E-TABM-163 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse presomitic mesoderm and somite-level tissue of 9.5 dpc Dll3 mutants
This SuperSeries is composed of the following subset Series:; GSE15152: MOE430A Analysis of Dll3 mutant vs. wild-type 9.5 dpc presomitic mesoderm; GSE15153: MOE430A Analysis of Dll3 mutant vs. wild-type 9.5 dpc somite-level tissue Experiment Overall Design: Refer to individual Series
ORGANISM(S): Mus musculus 
2009-03-14 | E-GEOD-15178 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouseDll3 mutant vs. wild-type 9.5 dpc presomitic mesoderm
Delta-like 3 (Dll3) is a divergent ligand and modulator of the Notch signaling pathway only identified so far in mammals. Null mutations of Dll3 disrupt cycling expression of Notch targets Hes1, Hes5, and Lfng, but not of Hes7. Compared with Dll1 or Notch1, the effects of Dll3 mutations are less se...
ORGANISM(S): Mus musculus 
2009-03-14 | E-GEOD-15152 | biostudies-arrayexpress
UnknownThe zebrafish presomitic mesoderm elongates through compaction-extension.
Not available
S-EPMC7612712 | biostudies-literature
GenomicsGenome wide occupancy of Msgn1 in differentiating embryonic stem cells
Msgn1 is a bHLH transcription factor and is a direct target gene of the Wnt/b-catenin signaling pathway. During mouse embryogenesis, Msgn1 is expressed in the mesodermal compartment of the primitive streak and is required for the differentiation of presomitic mesoderm. Msgn1-/- mutants show defects ...
ORGANISM(S): Mus musculus 
2014-09-04 | E-GEOD-55263 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Xenopus laevis developing notochord
We screened for differentially expressed genes in the developing notochord using the Affymetrix microarray system in Xenopus laevis. At late gastrula, we dissected four regions from the embryo, anterior mesoderm, posterior mesoderm, notochord and presomitic mesoderm. Three types of comparison were c...
ORGANISM(S): Xenopus laevis 
2006-12-31 | E-MEXP-717 | biostudies-arrayexpress
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