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TranscriptomicsThe global gene expression profile of superficial zone articular cartilage in P1 wildtype and Prg4 transgenic mice
To examine the unbiased global gene expression of over-expression of Prg4 in superficial zone articular chondrocytes in mice. This approach allows us to define novel signaling changes caused by the over-expression of Prg4 in superficial zone articular chondrocytes Total RNA was isolated from superf...
ORGANISM(S): Mus musculus 
2013-06-24 | E-GEOD-43663 | biostudies-arrayexpress
GenomicsCreb5 establishes the competence for Prg4 expression in articular cartilage
Creb5 establishes the competence for Prg4 expression in articular cartilage
PRJNA547776 | ENA
GenomicsscRNA-seq of Achilles tendons from Prg4-CreERT2 R26-tdTomato ATP mice
scRNA-seq of Achilles tendons from Prg4-CreERT2 R26-tdTomato ATP mice
PRJNA780190 | ENA
TranscriptomicsCreb5 establishes the competence for Prg4 expression in articular cartilage
Zhang et al. identify Creb5 as a transcription factor that is required for induction of Prg4 expression by TGFbeta and EGFR ligands. They show that Creb5 directly binds to two Prg4 promoter-proximal regulatory elements, working together with a more distal regulatory element to drive induction of Prg...
ORGANISM(S): Bos taurus 
2021-03-16 | GSE132379 | GEO
UnknownCreb5 establishes the competence for Prg4 expression in articular cartilage.
Not available
S-EPMC7955038 | biostudies-literature
UnknownIdentification of a Prg4-expressing articular cartilage progenitor cell population in mice.
Not available
S-EPMC4414823 | biostudies-literature
UnknownProteoglycan 4 (PRG4) expression and function in dry eye associated inflammation.
Not available
S-EPMC8491169 | biostudies-literature
UnknownProteoglycan 4 (PRG4) treatment enhances wound closure and tissue regeneration.
Not available
S-EPMC9232611 | biostudies-literature
UnknownFemur Shape Changes in Prg4-Deficient Mice: Morphological Insights Into Joint Well-Being.
Not available
S-EPMC12372646 | biostudies-literature
TranscriptomicsThe global gene expression profile of superficial zone articular cartilage in P1 wildtype and Prg4 transgenic mice
To examine the unbiased global gene expression of over-expression of Prg4 in superficial zone articular chondrocytes in mice. This approach allows us to define novel signaling changes caused by the over-expression of Prg4 in superficial zone articular chondrocytes
ORGANISM(S): Mus musculus 
2013-06-24 | GSE43663 | GEO
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