Sort   by:  
 Page size 
ProteomicsDeficiency of the ER protein seipin results in generalised lipodystrophy by incompletely understood mechanisms. Here, we report mitochondrial abnormalities in seipin deficient patient cells.Seipin localizes at endoplasmic reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes
Deficiency of the ER protein seipin results in generalised lipodystrophy by incompletely understood mechanisms. Here, we report mitochondrial abnormalities in seipin deficient patient cells. A subset of seipin is enriched at ER-mitochondria contact sites (MAMs) in human and mouse cells and localizes...
ORGANISM(S): Mus musculus (Mouse) 
2022-01-18 | PXD029637 | Pride
Ap-ms Mus musculus Seipin Calcium handling Adipocyte Orbitrap fusion Bottom-up Mams Mitochondria dysfunction 
UnknownStructural and chemical insights on the incorporation of americium into zircaloy-derived monoclinic zirconia.
Not available
S-EPMC12847942 | biostudies-literature
UnknownPolymorphic Microsatellite Markers for the Tetrapolar Anther-Smut Fungus Microbotryum saponariae Based on Genome Sequencing.
Not available
S-EPMC5104459 | biostudies-literature
TranscriptomicsMicroarray analysis of normal and tumor-like bone cells from neonatal-onset multisystem inflammatory disease (NOMID)
We analyzed the whole transcriptome profiling of NOMID normal and tumor-like bone cells Total RNA obtained from NOMID bone tumor culture was compared to NOMID normal cartilage cells established from the same patient.
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-21835 | biostudies-arrayexpress
UnknownTPV1, the first virus isolated from the hyperthermophilic genus Thermococcus.
Not available
S-EPMC5935114 | biostudies-literature
TranscriptomicsDifferential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice.
Obesity-associated insulin resistance is characterized by a state of chronic, low-grade inflammation that is associated with the accumulation of M1 proinflammatory macrophages in adipose tissue. Although different evidence explains the mechanisms linking the expansion of adipose tissue and adipose t...
ORGANISM(S): Mus musculus 
2012-03-22 | E-GEOD-36669 | biostudies-arrayexpress
MetabolomicsStrong effect of Penicillium roqueforti populations on volatile and metabolic compounds responsible for aromas, flavour and texture in blue cheeses
Studies of food microorganism domestication can provide important insight into adaptation mechanisms and lead to commercial applications. Penicillium roqueforti is a fungus with four genetically differentiated populations, two of which were independently domesticated for blue cheese-making, with the...
2021-10-06 | MTBLS1509 | MetaboLights
UnknownChronic Infantile Neurological Cutaneous and Articular (CINCA) syndrome: a review.
Not available
S-EPMC5142346 | biostudies-literature
TranscriptomicsInduced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery
Chronic infantile neurological cutaneous and articular (CINCA) syndrome is an IL-1-driven autoinflammatory disorder caused mainly by NLRP3 mutations. The pathogenesis of CINCA syndrome patients who carry NLRP3 mutations as somatic mosaicism has not been precisely described because of the difficulty ...
ORGANISM(S): Homo sapiens 
2012-06-10 | E-GEOD-38626 | biostudies-arrayexpress
UnknownThe p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase.
Not available
S-EPMC151332 | biostudies-literature
Sort   by:  
 Page size