Purpose: To explore the plasma metabolite profiles of patients with early primary angle-closure glaucoma (PACG) and investigate their relevance to ocular characteristics and retinal-associated parameters.
Methods:Plasma samples were obtained from 30 early PACG patients and 30 healthy contro...
This study focuses on the Helan Mountain East Foothills region of Ningxia, a typical continental climate wine-growing area, with Cabernet Sauvignon grapes as the subject. It combines trime-thylsilyl derivatization -Gas Chromatography-Mass Spectrometry (TMS-GC-MS) technology and the independently ...
Abstract
Background: Primary idiopathic male infertility (PIMI) is a complex condition with unclear biological mechanisms. Increasing evidence indicates that gut microbiome-derived functional and metabolic alterations can influence host physiological processes, yet microbiome-associated fun...
Primary immune thrombocytopenia (ITP) is recognized as an acquired autoimmune hemorrhagic disorder distinguished by diminished platelet counts. The efficacy of a sex-stratified multi-omics integrative analytical strategy for forecasting pediatric ITP chronicity was proposed and validated in this ...
Osteocytes could release some small molecules (≤ 1 kDa) through gap junctions and hemichannels to extracellular environment, such as prostaglandin E2 (PGE2), nitric oxide (NO) and adenosine triphosphate (ATP), which play key roles in transferring signals between bone cells and other tissue cells....
Metastatic breast tumors must adapt to the metabolic constraints of their target tissues. To understand how tumor metabolism varies across sites, we compared glucose utilization in primary mammary fat pad (MFP) tumors and brain metastases derived from the breast cancer cell line MDA-MB-231. Tumor...