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ProteomicsPrimary mouse embryonic palatal mesenchyme LC-MS/MS
To identify proteins phosphorylated by Akt downstream of PI3K-mediated PDGFRalpha signaling, we immunoprecipitated Akt phosphorylation substrates from PDGF-AA-treated primary mouse embryonic palatal mesenchyme (MEPM) lysates and analyzed the peptides by nano LC-MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2019-06-04 | PXD000779 | Pride
Mouse Primary embryonic palatal mesenchyme Lc-ms/ms 
TranscriptomicsGene expression profiling of primary mouse embryonic palatal mesenchymal cells in Tgfbr2 mutant mouse models
The overall goal of this project is to investigate the role of TGF-beta signaling in regulating the cellular metabolism of cranial neural crest (CNC) cells during palate development. Here, we conducted gene expression profiling of primary mouse embryonic palatal mesenchymal (MEPM) cells from wild ty...
ORGANISM(S): Mus musculus 
2013-10-01 | E-GEOD-46150 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of the palate in Erk2 mutant mouse models
The overall goal of this project is to investigate the role of Erk2-mediated signaling in regulating the cellular metabolism of cranial neural crest (CNC) cells during palate development. Here, we conducted gene expression profiling of palate tissue from wild type mice as well as those with a neural...
ORGANISM(S): Mus musculus 
2015-12-11 | E-GEOD-67087 | biostudies-arrayexpress
UnknownSPECC1L-deficient primary mouse embryonic palatal mesenchyme cells show speed and directionality defects.
Not available
S-EPMC7809270 | biostudies-literature
UnknownAnti-epileptic drug topiramate upregulates TGFβ1 and SOX9 expression in primary embryonic palatal mesenchyme cells: Implications for teratogenicity.
Not available
S-EPMC7880431 | biostudies-literature
TranscriptomicsGene expression profiling of Tgfbr2 mutant mouse models of cleft palate
The overall goal of this project is to investigate the role of TGF-beta signaling in palate development in order to discover candidate therapeutics for preventing and treating congenital birth defects. Here, we conducted gene expression profiling of embryonic palatal tissue from wild type mice as we...
ORGANISM(S): Mus musculus 
2011-11-29 | E-GEOD-22989 | biostudies-arrayexpress
UnknownTransforming Growth Factor-Beta and Sonic Hedgehog Signaling in Palatal Epithelium Regulate Tenascin-C Expression in Palatal Mesenchyme During Soft Palate Development.
Not available
S-EPMC7287209 | biostudies-literature
TranscriptomicsLoss of p130Cas impairs palatal mesenchymal expansion and causes cleft palate
Palatogenesis is a complex developmental process requiring coordinated growth, elevation, and fusion of the palatal shelves. Disruption of these events results in cleft palate, one of the most common congenital craniofacial anomalies. p130Crk-associated substrate (p130Cas) is an adaptor protein invo...
ORGANISM(S): Mus musculus 
2026-04-07 | GSE326799 | GEO
GenomicsLoss of p130Cas impairs palatal mesenchymal expansion and causes cleft palate
Loss of p130Cas impairs palatal mesenchymal expansion and causes cleft palate
PRJNA1447366 | ENA
GenomicsMus musculus
Gene expression profiling of primary mouse embryonic palatal mesenchymal cells in Tgfbr2 mutant mouse models
PRJNA197373 | ENA
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