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ProteomicsHuman osteoblasts quantitative proteomic analysis after cocultivation with endothelial cells
We previously described that the coculture of primary human osteoblasts (hOBs) and human umbilical vein endothelial cells (HUVECs) improves the differentiation of both cell types, leading to the formation of functional blood vessels and enhanced bone regeneration. The objective of this study was to ...
ORGANISM(S): Homo sapiens (Human) 
2018-12-03 | PXD011844 | Pride
Primary human osteoblasts (hobs) Angiogenesis Bone tissue engineering Stable isotope labeling by amino acids in cell culture (silac) Human umbilical vein endothelial cells (huvecs) Quantitative proteomics 
TranscriptomicsTranscription profiling of human osteoblast transcriptome in resting and induced primary cells
Osteoblasts are key players in bone remodeling. The accessibility of human primary osteoblast-like cells (HOb) from bone explants render them a lucrative model for studying molecular physiology of bone turnover, discovery of novel anabolic therapeutics and mesenchymal cell biology in general. Relati...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-10311 | biostudies-arrayexpress
TranscriptomicshOB Transcriptome after HUVEC-Cocultivation
Vascularization represents an important issue in bone development, fracture healing and engineering of artificial bone tissue. In the context of bone tissue engineering, it was shown that coimplantation of human primary umbilical vein endothelial cells (HUVECs) and human osteoblasts (hOBs) results i...
ORGANISM(S): Homo sapiens 
2015-12-17 | E-MTAB-4152 | biostudies-arrayexpress
TranscriptomicsExpression profiles of human primary osteoblasts (HOB) and MET transformed osteoblast clones
We studied MET-transformed human primary osteoblasts (MET-HOBs), which we previously turned into osteosarcoma cells by LV driven over-expression of MET oncogene. We obtained distinct MET transformed HOB clones derived from independent events of transgene integration. To characterise the phenotype of...
ORGANISM(S): Homo sapiens 
2013-02-28 | GSE28256 | GEO
TranscriptomicsExpression profiles of human primary osteoblasts (HOB) and MET transformed osteoblast clones
We studied MET-transformed human primary osteoblasts (MET-HOBs), which we previously turned into osteosarcoma cells by LV driven over-expression of MET oncogene. We obtained distinct MET transformed HOB clones derived from independent events of transgene integration. To characterise the phenotype o...
ORGANISM(S): Homo sapiens 
2013-02-28 | E-GEOD-28256 | biostudies-arrayexpress
UnknownThe dose-dependent impact of γ-radiation reinforced with backscatter from titanium on primary human osteoblasts.
Not available
S-EPMC10190184 | biostudies-literature
UnknownVitamin D activation of functionally distinct regulatory miRNAs in primary human osteoblasts.
Not available
S-EPMC3663893 | biostudies-literature
GenomicsHomo sapiens
Expression profiles of human primary osteoblasts (HOB) and MET transformed osteoblast clones
PRJNA139567 | ENA
TranscriptomicsSystematic Assessment of Human Osteoblast Transcriptome in Resting and Induced Primary Cells
Osteoblasts are key players in bone remodeling. The accessibility of human primary osteoblast-like cells (HOb) from bone explants render them a lucrative model for studying molecular physiology of bone turnover, discovery of novel anabolic therapeutics and mesenchymal cell biology in general. Relati...
ORGANISM(S): Homo sapiens 
2008-02-01 | GSE10311 | GEO
GenomicExpression QTL (eQTL) Analysis in Human Primary Cells

The common genetic variants associated with complex traits typically lie in non-coding DNA and may alter gene regulation in a cell type-specific manner. Consequently, the choice of tissue or cell model in the dissection of disease associations is important. We carried out an expression quanti...

phs000225 | dbGaP
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