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MetabolomicsAn Atlas of Ferroptosis-induced Secretomes promotes Macrophage priming
Cells undergoing regulated necrosis systemically communicate with the immune system via release of protein and non-protein secretomes. Ferroptosis is a recently described iron-dependent type of regulated necrosis driven by massive lipid peroxidation. While membrane rupture occurs during ferroptosis,...
2025-03-04 | MTBLS9798 | MetaboLights
MetabolomicsMetabolic signatures of Arabidopsis thaliana abiotic stress responses elucidate patterns in stress priming, acclimation, and recovery

Temperature, water and light are 3 abiotic stress factors that have major influences on plant growth, development and reproduction. Plants can be primed by a prior mild stress to enhance their resistance to future stress. We used an untargeted metabolomics approach to examine Arabidopsis thal...

2022-05-30 | MTBLS3672 | MetaboLights
MetabolomicsCell of origin epigenetic priming determines susceptibility to Tet2 mutation

Hematopoietic stem cell (HSC) mutations can result in clonal hematopoiesis (CH) with heterogeneous clinical outcomes. Here, we investigated how the cell state preceding Tet2 mutation impacts the pre-malignant phenotype. Using an inducible system for clonal analysis of myeloid progenitors...

2024-04-30 | MTBLS9914 | MetaboLights
MetabolomicsUltrasound Priming Enhances Seed Vigor and Multiple Stresses Tolerance in Aged Maize Seeds

Seed aging leads to reduced germination rates and vigor, particularly under stress conditions. We subjected aged maize seeds to 40 seconds of ultrasonic treatment, which enhanced their vigor and tolerance to combined stress. The ultrasonic treatment increased more cracks and holes in the seed coa...

2026-03-25 | MTBLS14138 | MetaboLights
MetabolomicsUltrasound Priming Enhances Seed Vigor and Multiple Stresses Tolerance in Aged Maize Seeds
Seed vigor plays a crucial role in germination rate, population uniformity, seedling stress resistance and potential yield at maturity. Here we report a simple, eco-friendly physical method (40-second ultrasound) that rapidly triggers aged seeds to enhance seed vigor and stress resistance. Significa...
2026-07-15 | MTBLS15047 | MetaboLights
ModelsStress priming and thermotolerance model - Pfeuty et al. 2021
The model describes cellular adaptation to proteotoxic stress through four dynamical variables: protein damage, cell survival, molecular chaperone mRNA and molecular chaperone protein. Heat increases the production of misfolded proteins, which are either degraded or repaired by chaperones. Accumulat...
2026-09-02 | MODEL2608180005 | BioModels
ModelsWodarz2003 - Cytotoxic T lymphocyte cross-priming
This a model from the article: A dynamical perspective of CTL cross-priming and regulation: implications for cancer immunology. Wodarz D, Jansen VA. Immunol Lett 2003 May 1;86(3):213-27 12706524 , Abstract: ...
2024-09-02 | BIOMD0000000685 | BioModels
TranscriptomicsMulti-Targeted Priming For Genome-Wide Gene Expression Assays
This SuperSeries is composed of the following subset Series: GSE22658: Neurospora crassa early sexual development with MTP priming GSE22936: Saccharomyces cerevisiae grown in nitrogen depletion with MTP priming GSE22972: Neurospora crassa early sexual development with oligod(T) priming GSE22992: Sac...
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-20 | E-GEOD-23003 | biostudies-arrayexpress
TranscriptomicsSaccharomyces cerevisiae grown in nitrogen depletion with MTP priming
Multi-targeting priming (MTP) for genome-wide gene expression assays provides selective targeting of multiple sequences and counter-selection against undesirable sequences. We demonstrated superior performance of two MTPs compared to oligo-dT microarray profling and RNA tag sequencing the response o...
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-17 | E-GEOD-22936 | biostudies-arrayexpress
TranscriptomicsNeurospora crassa early sexual development with oligod(T) priming
Multi-targeting priming (MTP) for genome-wide gene expression assays provides selective targeting of multiple sequences and counter-selection against undesirable sequences. We demonstrated superior performance of two MTPs compared to oligo-dT microarray profling and RNA tag sequencing the response o...
ORGANISM(S): Neurospora crassa 
2010-07-17 | E-GEOD-22972 | biostudies-arrayexpress
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