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MetabolomicsComprehensive quality standardization of Haizhixiaolin capsules via multi-component fingerprinting and metabolomic
Haizhixiaolin Capsule (HZXL), a traditional Chinese medicine hospital preparation for treating chronic prostatitis and urinary disorders, consists of ten herbal components. Due to the complexity of its multi-component nature, establishing a robust quality control system remains challenging. This stu...
2026-03-26 | MTBLS14148 | MetaboLights
MetabolomicsLipids in the escalated host-pathogen arms race

Lipids, fundamental constituents of cell membranes, cellular energy carriers, and signaling molecules, play a pivotal role in the interaction between pathogens and hosts. During microbial infections, lipids not only fuel the activation of the immune system but also, acting as signaling molec...

2025-07-05 | MTBLS12678 | MetaboLights
TranscriptomicspcaGoPromoter - An R package for functional interpretation of principal component analysis of genome-wide gene expression data
Background and aim: Analysis of data obtained from genome wide gene expression experiments is challenging, due to the huge amount of variables, management of the data and the need for multivariate analysis. We here present the R package: pcaGoPromoter that facilitates the interpretation of genome wi...
ORGANISM(S): Homo sapiens 
2011-05-01 | E-GEOD-27071 | biostudies-arrayexpress
MetabolomicsMetabolomics-Driven Discovery of an Introduced Species and Two Malaysian Piper betle L. Variants
The differences in pungency of 'sirih' imply the probable occurrence of several variants of Piper betle L. in Malaysia. However, the metabolite profiles underlying the pungency of the different variants remain a subject of further research. The differences in metabolite profiles of selected M...
2022-03-21 | MTBLS2585 | MetaboLights
MetabolomicsLipidomic analysis of lipid droplets from murine hepatocytes reveals distinct signatures for nutritional stress
Liver steatosis can be induced by fasting or high-fat diet. We investigated by lipidomic analysis whether such metabolic states are reflected in the lipidome of hepatocyte lipid droplets (LDs) from mice fed normal chow diet (FED), fasted (FAS), or fed a high-fat diet (HFD). LC-MS/MS at levels of lip...
2014-08-19 | MTBLS26 | MetaboLights
OtherPRINCIPAL COMPONENT ANALYSIS FOR EXPERIMENTS
Although principal component analysis is frequently used in multivariate/ analysis, it has disadvantages when applied to experimental or diagnostic data. First, the identified principal components have poor generality; since the size and directions of the components are dependent on the particular d...
ORGANISM(S): Mus musculus Rattus norvegicus 
2011-08-15 | GSE31375 | GEO
MetabolomicsUntargeted metabolomic analysis in cats with naturally occurring inflammatory bowel disease and alimentary small cell lymphoma
Feline chronic enteropathy (CE) is a common gastrointestinal disorder in cats and mainly comprises inflammatory bowel disease (IBD) and small cell lymphoma (SCL). Differentiation between IBD and SCL can be diagnostically challenging. We characterized the fecal metabolome of 14 healthy cats and 22 ca...
2021-07-13 | MTBLS440 | MetaboLights
UnknownSparse principal component analysis by choice of norm.
Not available
S-EPMC3601508 | biostudies-literature
ProteomicsAn automated intact glycopeptide enrichment method for serum site-specific N-glycoproteomic analysis
We developed an automated glycopeptide enrichment method for the analysis of serum site-specific N-glycoproteome. This automated method allowed for processing one sample within 20 min. It showed higher enrichment specificity, more intact glycopeptide identifications, and better quantitative reproduc...
ORGANISM(S): Homo Sapiens (human) 
2021-04-06 | PXD025151 | JPOST Repository
MetabolomicsScreening of Differential Metabolites and Metabolic Pathway Analysis Related to Colorectal Adenoma Recurrence

Background To analyze the differences in gut metabolites between the CRA (colorectal adenoma) recurrence and non-recurrence groups, to identify characteristic metabolites and related metabolic pathways associated with recurrence, and to provide new evidence for risk stratification and interv...

2026-08-08 | MTBLS15298 | MetaboLights
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