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UnknownAmiR-P3: An AI-based microRNA prediction pipeline in plants.
Not available
S-EPMC11293646 | biostudies-literature
TranscriptomicsGenomic analysis of hESC pedigrees enables identification of de novo genetic alterations and determination of the timing and origin of mutational events
Given the association between mutational load and cancer, the observation that genetic aberrations are frequently found in human pluripotent stem cells (hPSCs) is of concern. Prior studies in hiPSCs have shown that deletions and regions of loss-of-heterozygosity (LOH) tend to arise during reprogramm...
ORGANISM(S): Homo sapiens 
2014-04-21 | E-GEOD-49452 | biostudies-arrayexpress
MetabolomicsMetabolomics Characterization of Human Calcific Aortic Valve Stenosis

BACKGROUND: Calcific aortic valve stenosis (CAVS) is the most prevalent valvular heart disease in developed countries with significant morbidity and mortality. Given the poor understanding of the pathophysiological processes leading to CAVS, we utilized a joint non-targeted metab...

2020-02-03 | MTBLS1267 | MetaboLights
ProteomicsIRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy
Stochastic transition of cancer cells between drug-sensitive and drug-tolerant persister phenotypes has been proposed to play a key role in non-genetic resistance to therapy. Yet, we show here that cancer cells actually possess a highly stable inherited chance to persist (CTP) during therapy. This C...
ORGANISM(S): Homo sapiens (Human) 
2021-08-10 | PXD026857 | Pride
Irs1 Drug tolerant cells Drug resistance Cancer peristers Egfr inhibition Nsclc Cancer 
ProteomicsIRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy
Stochastic transition of cancer cells between drug-sensitive and drug-tolerant persister phenotypes has been proposed to play a key role in non-genetic resistance to therapy. Yet, we show here that cancer cells actually possess a highly stable inherited chance to persist (CTP) during therapy. This C...
ORGANISM(S): Homo sapiens (Human) 
2021-08-10 | PXD026844 | Pride
Irs1 Drug tolerant cells Drug resistance Cancer peristers Egfr inhibition Nsclc Cancer 
ProteomicsIRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy
Stochastic transition of cancer cells between drug-sensitive and drug-tolerant persister phenotypes has been proposed to play a key role in non-genetic resistance to therapy. Yet, we show here that cancer cells actually possess a highly stable inherited chance to persist (CTP) during therapy. This C...
ORGANISM(S): Homo sapiens (Human) 
2021-08-10 | PXD026824 | Pride
Irs1 Drug tolerant cells Drug resistance Cancer peristers Egfr inhibition Nsclc Cancer 
ProteomicsIRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy
Stochastic transition of cancer cells between drug-sensitive and drug-tolerant persister phenotypes has been proposed to play a key role in non-genetic resistance to therapy. Yet, we show here that cancer cells actually possess a highly stable inherited chance to persist (CTP) during therapy. This C...
ORGANISM(S): Homo sapiens (Human) 
2021-08-10 | PXD026805 | Pride
Irs1 Drug tolerant cells Drug resistance Cancer peristers Egfr inhibition Nsclc Cancer 
ProteomicsIRS1 phosphorylation underlies the non-stochastic probability of cancer cells to persist during EGFR inhibition therapy
Stochastic transition of cancer cells between drug-sensitive and drug-tolerant persister phenotypes has been proposed to play a key role in non-genetic resistance to therapy. Yet, we show here that cancer cells actually possess a highly stable inherited chance to persist (CTP) during therapy. This C...
ORGANISM(S): Homo sapiens (Human) 
2021-08-10 | PXD026842 | Pride
Irs1 Drug tolerant cells Drug resistance Cancer peristers Egfr inhibition Nsclc Cancer 
TranscriptomicsChanges in cardiac transcription profiles following off-pump coronary revascularization surgery
To investigate changes in cardiac transcription profiles caused by off-pump cardiac surgery, we collected myocardial samples, prior and after grafting, from patients undergoing off-pump coronary revascularization surgery. The transcriptional profile of the mRNA in these samples was measured with gen...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-12485 | biostudies-arrayexpress
TranscriptomicsChanges in cardiac transcription profiles following on-pump coronary artery bypass grafting
To investigate changes in cardiac transcription profiles caused by on-pump cardiac surgery, we collected myocardial samples, prior and after grafting, from patients undergoing on-pump coronary artery bypass grafting with cardiopulmonary bypass and cardiac arrest. The transcriptional profile of the m...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-12486 | biostudies-arrayexpress
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