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MetabolomicsLipidOA: A Machine-Learning and Prior-Knowledge-Based Tool for Structural Annotation of Glycerophospholipids
The Paternò-Büchi (PB) reaction is a carbon-carbon double bond (C═C)-specific derivatization reaction that can be used to pinpoint the location(s) of C═C(s) in unsaturated lipids and quantitate the location of isomers when coupled with tandem mass spectrometry (MS/MS). As the data of PB-MS/MS are in...
2022-11-23 | MTBLS6075 | MetaboLights
GenomicsY-chromosome capture of ancient human samples
In-solution Y-chromosome capture-enrichment on ancient DNA libraries
PRJEB23498 | ENA
MetabolomicsNMR based metabolomics study of Y2 receptor activation by neuropeptide Y in the SK-N-BE2 human neuroblastoma cell line
Neuropeptide Y (NPY) and its Y2 receptors (Y2R) play an important role in regulating growth of various tumors and are highly expressed in human neuroblastoma brain tumors. Cell lines derived from neuroblastoma brain tumors provide a good model to study the consequences of NPY activation of Y2R in tu...
2014-10-01 | MTBLS104 | MetaboLights
TranscriptomicsTranscription profiling of mouse Peyers patch and mesenteric lymph nodes after oral infection with Y. enterolitica
To gain a comprehensive view of the host response to pathogens within these tissues, we determined the transcriptional profiles of intestinal lymphatic tissue infected with Y. enterocolitica. Expression analysis using Affymetrix GeneChips revealed a complex host response in the Peyer’s patches (PP) ...
ORGANISM(S): Mus musculus 
2007-11-24 | E-GEOD-4764 | biostudies-arrayexpress
ProteomicsCrocodile Sperm Proteome
In a reproductive strategy that is considered unique to the mammalian lineage, spermatozoa must undergo a series of physiological changes, termed capacitation, in the female reproductive tract prior to developing their capacity to fertilize an ovum. Here, we have employed a comparative proteomic str...
ORGANISM(S): Crocodylus Porosus (ncbitaxon:8502) 
2018-04-08 | MSV000082258 | MassIVE
GenomicsY-27632 and radiation treatment of patient-derived GBM cells
Y-27632- or vehicle-treated GBM1 cells 5 days after 0 or 20 Gy irradiation
PRJEB26811 | ENA
ProteomicsQuest for missing proteins in the human spermatozoa: an update
Here, we report work as part of C-HPP initiatives on chromosomes 14 (France) and 2 (Switzerland) aiming to identify missing proteins in ejaculated human spermatozoa using multiple MS-based and antibodies-based validation approaches
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080826 | MassIVE
ProteomicsDDX3Y and other Male Specific Region of Y Chromosome Genes may modulate neuronal differentiation and mediate various biological pathways in addition to their well described role regulating spermatogenesis
Human tissue based proteomics projects are challenging due to low abundance of proteins and tissue specificity of protein expression. In this study, we aimed to develop a cell-based approach to profile the male specific region of the Y chromosome (MSY) proteins. First, we profiled the expression of ...
ORGANISM(S): Homo sapiens (Human) 
2015-09-17 | PXD002428 | Pride
Rna metabolism. Chromosome centric human proteome project (c-hpp) Ddx3y Apoptosis Cell-based human proteome project Cell cycle Shotgun proteomics Y-linked genes 
TranscriptomicsY. pestis KIM6+ TraSH Microarray Analysis After Intracellular Replication
The transposon site hybridization (TraSH) technique (Sassetti, CM et al. 2001. PNAS 98:12712-7) was utilized to identify genes important for the survival of Y. pestis within murine macrophages. A transposon library was created with ~31,500 Y. pestis KIM6+ insertion mutants. A portion of the Y. pes...
ORGANISM(S): Yersinia pestis 
2011-11-30 | E-GEOD-33982 | biostudies-arrayexpress
ProteomicsComparative proteomics of Trypanosoma cruzi Y and VFRA strains.
Chagas disease is one of the most lethal diseases in Latin America, but currently it has become a global health problem because of migration. It is caused by the parasite Trypanosoma cruzi (T. cruzi), an intracellular flagellated protist whose life cycle has been defined in detail, although the immu...
ORGANISM(S): Trypanosoma cruzi 
2019-09-25 | PXD012536 | Pride
Antioxidant defenses. Chagas disease Trypomastigote Replication Proteome Gene ontology Trypanosoma cruzi Enriched metabolic pathways 
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