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TranscriptomicsTranscriptional single-cell study of Nanoparticle-derived TR1-like cells in NOD.Prdm1 flox/floxCD4-Cre+ mice.
10X technology single-cell RNA-seq was used on tetramer-sorted CD4+ T cells from nanoparticle-treated control mice (NOD.CD4-Cre+ and NOD.Prdm1 flox/flox) and NOD.Prdm1 flox/floxCD4-Cre+ mice to study the role of Prmd1 on the differentiation of TFH cells into TR1 cells. Study evidencies the devolopme...
ORGANISM(S): Mus musculus 
2023-03-27 | GSE182636 | GEO
GenomicsTranscriptional single-cell study of Nanoparticle-derived TR1-like cells in NOD.Prdm1 flox/floxCD4-Cre+ mice.
Transcriptional single-cell study of Nanoparticle-derived TR1-like cells in NOD.Prdm1 flox/floxCD4-Cre+ mice.
PRJNA757242 | ENA
UnknownNonO Is a Novel Co-factor of PRDM1 and Regulates Inflammatory Response in Monocyte Derived-Dendritic Cells.
Not available
S-EPMC7378894 | biostudies-literature
UnknownA capture-sequencing strategy identifies IRF8, EBF1, and APRIL as novel IGH fusion partners in B-cell lymphoma.
Not available
S-EPMC3731929 | biostudies-literature
TranscriptomicsIdentification of a transcription factor network that regulates anti-TNF mediated IL-10 expression in human CD4+ T-cells
CD4+ T-cells are key players in the pathogenesis of rheumatoid arthritis (RA) through potent production of inflammatory mediators including IL-17A, IFNg and TNF. Anti-TNF therapy has revolutionized the treatment of RA and we previously demonstrated that in vitro treatment of human CD4+ T-cells with ...
ORGANISM(S): Homo sapiens 
2024-09-25 | GSE216688 | GEO
ProteomicsKey regulatory roles of PRDM1 in human NK-cell differentiation and activation
PRDM1, encoding a transcription factor (TF), regulates plasma cell and CD8+ T-cell terminal differentiation and Th2 lineage specification, while its role in human NK-cell differentiation and homeostasis is largely unknown. Here, we employed a multi-omics approach to dissect the transcriptional contr...
ORGANISM(S): Homo sapiens (Human) 
2026-01-19 | PXD069044 | Pride
Prmd1 Mass spectrometry Proximity labeling Nk-cells 
TranscriptomicsCNV PCNSL
Primary central nervous system lymphomas (PCNSL) are extranodal non-Hodgkin lymphomas arising within brain, spine cord or eyes and represent approximately 3% of all primary brain tumors in adults. PCNSL are histologically homogeneous- more than 90% are diffuse large B cell lymphomas - but clinically...
ORGANISM(S): Homo sapiens 
2015-02-26 | E-MTAB-1905 | biostudies-arrayexpress
GenomicsIdentification of a transcription factor network that regulates anti-TNF mediated IL-10 expression in human CD4+ T-cells
Identification of a transcription factor network that regulates anti-TNF mediated IL-10 expression in human CD4+ T-cells
PRJNA894970 | ENA
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