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UnknownExosomes from HIV-1-infected Cells Stimulate Production of Pro-inflammatory Cytokines through Trans-activating Response (TAR) RNA.
Not available
S-EPMC4714213 | biostudies-literature
TranscriptomicsGene expression of TCR-alpha/beta CD4- CD8- human T cells
The origin and function of human double negative (DN) TCR-alpha/beta T cells is unknown. They are thought to contribute to the pathogenesis of systemic lupus erythematosus because they expand and accumulate in inflamed organs. Here we provide evidence that human TCR-alpha/beta CD4- CD8- DN T cells...
ORGANISM(S): Homo sapiens 
2009-05-16 | E-GEOD-16130 | biostudies-arrayexpress
TranscriptomicsCCRF-CEM Prednisolone treatment at 4h
Background: Glucocorticoids are important pharmaceutical agents in the treatment of acute lymphoblastic leukemia in children. Resistance or sensitivity to glucocorticoids is considered to be of crucial importance for disease prognosis. Prednisolone is a first-line chemotherapeutic agent in the treat...
ORGANISM(S): Homo sapiens 
2011-03-22 | E-GEOD-27989 | biostudies-arrayexpress
UnknownMicroRNA-146a rs2910164 is associated with severe preeclampsia in Black South African women on HAART.
Not available
S-EPMC5248445 | biostudies-literature
TranscriptomicsTranscription profiling by array of bovine gene expression changes during inflammatory gamma-herpesvirus infection
Changes in gene expression in lymph node and kidney of cattle infected with alcelaphine herpesvirus-1. All animals in the group infected with AlHV-1 showed clinical signs of Malignant catarrhal fever (MCF) within one month. Diagnosis of MCF in these animals was confirmed by diagnostic PCR. No clin...
ORGANISM(S): Bos taurus 
2012-10-26 | E-MEXP-3497 | biostudies-arrayexpress
TranscriptomicsEvidence of an Increased Pathogenic Footprint in the Lingual Microbiome of Untreated HIV Infected Patients
Opportunistic oral infections are ultimately presented in a vast majority of HIV-infected patients, often causing debilitating lesions that also contribute to deterioration in nutritional health. Although appreciation for the role that the microbiota is likely to play in the initiation and/or enhan...
ORGANISM(S): Homo sapiens 
2012-06-25 | E-GEOD-38908 | biostudies-arrayexpress
TranscriptomicsIn Vivo Mapping of Arabidopsis Scaffold/Matrix Attachment Regions Reveals Link to Nucleosome-Disfavoring Poly(dA:dT) Tracts
Scaffold or matrix attachment regions (S/MARs) are found in all eukaryotes. The pattern of distribution and genomic context of S/MARs is thought to be important for processes such as chromatin organization and modulation of gene expression. Despite the importance of such processes, much is unknown a...
ORGANISM(S): Arabidopsis thaliana 
2014-02-03 | E-GEOD-45549 | biostudies-arrayexpress
ProteomicsPathogenic Natural Antibodies Recognizing Annexin IV Are Required to Develop Intestinal Ischemia-Reperfusion Injury
Intestinal ischemia-reperfusion (IR) injury is initiated when natural IgM antibodies recognize neo-epitopes that are revealed on ischemic cells. The target molecules and mechanisms whereby these neo-epitopes become accessible to recognition are not well understood. Proposing that isolated intestinal...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-14862 | biostudies-arrayexpress
TranscriptomicsArabidopsis thaliana chromosome 4 replicates in two phases that correlate with chromatin state
DNA replication programs have been studied extensively in yeast and animal systems, where they have been shown to correlate with gene expression and certain epigenetic modifications. Despite the conservation of core DNA replication proteins, little is known about replication programs in plants. We u...
ORGANISM(S): Arabidopsis thaliana 
2011-07-06 | E-GEOD-30433 | biostudies-arrayexpress
TranscriptomicsRadiation response in xenografts of the head and neck cancer UT14 cell line
Low passage head and neck squamous cancer cells (UT-14-SCC) were injected into the flanks of female nu/nu mice to generate xenografts. After tumors reached a size of 500mm3, they were treated with either sham RT or 15 Gy in one fraction. At different time points, days 0, 3, 10 and for controls and d...
ORGANISM(S): Homo sapiens 
2014-09-19 | E-GEOD-61573 | biostudies-arrayexpress
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