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MetabolomicsProbabilistic networks of blood metabolites in healthy subjects as indicators of latent cardiovascular risk
The complex nature of the mechanisms behind cardiovascular diseases prevents the detection of latent early risk conditions. Network representations are ideally suited to investigate the complex interconnections between the individual components of a biological system underlying complex diseases. Her...
2015-01-01 | MTBLS147 | MetaboLights
ModelsCeliku_Friedenberg_2022 -- Probabilistic Model Checking of Cancer Metabolism
We provide a model of glycolysis and TCA cycle in cancers in which IDH is encountered both in its wild type form as well as mutated and capable of catalyzing an onco-metabolite. The model is constructed using the Probabilistic Symbolic Model Checker (PRISM,https://www.prismmodelchecker.org/) specifi...
2022-07-18 | MODEL2207180001 | BioModels
GenomicsContinuous-trait probabilistic model for comparing multi-species functional genomic data
Continuous-trait probabilistic model for comparing multi-species functional genomic data
PRJNA437983 | ENA
MetabolomicsMetabolic profiling of maternal serum of women at high-risk of spontaneous preterm birth using NMR and MGWAS approach
Preterm birth (PTB) is a leading global cause of infant mortality. Risk factors include genetics, lifestyle choices and infection. Understanding the mechanism of PTB could aid the development of novel approaches to prevent PTB. This study aimed to investigate the metabolic biomarkers of PTB in early...
2023-05-24 | MTBLS1990 | MetaboLights
GenomicsVIPR: A probabilistic algorithm for analysis of microbial detection microarrays
VIPR: A probabilistic algorithm for analysis of microbial detection microarrays
PRJNA126409 | ENA
GenomicsA Probabilistic Model of Transcription Dynamics applied to Estrogen Signalling in Breast Cancer Cells
Gene transcription mediated by RNA polymerase II (pol-II) is a key step in gene expression. The dynamics of pol-II moving along the transcribed region influences the rate and timing of gene expression. In this work we present a probabilistic model of transcription dynamics which is f...
ORGANISM(S): Homo sapiens 
2014-05-19 | E-GEOD-44800 | biostudies-arrayexpress
ProteomicsMetaNovo : an open-source pipeline for probabilistic peptide discovery in complex metaproteomic datasets
Results We compared MetaNovo to published results from the MetaPro-IQ pipeline on 8 human mucosal-luminal interface samples, with comparable numbers of peptide and protein identifications, many shared peptide sequences and a similar bacterial taxonomic distribution compared to that found using a ma...
ORGANISM(S): human gut metagenome 
2023-05-16 | PXD030708 | Pride
Metaproteomics De novo sequencing Probabilistic 
GenomicsEpiclomal: probabilistic clustering of sparse single-cell DNA methylation data
We present Epiclomal, a probabilistic clustering method arising from a hierarchical mixture model to simultaneously cluster sparse single-cell DNA methylation data and infer their corresponding hidden methylation profiles. Using synthetic and published single-cell CpG datasets we show that Epiclomal...
EGAS00001003504 | EGA
OtherContinuous-trait probabilistic model for comparing multi-species functional genomic data
We developed a probabilistic method to simultaneously infer genome-wide heterogeneous evolutionary states. We applied the proposed method to analyze a cross-species DNA replication timing (RT) dataset from the same cell type in five primate species. We demonstrated that the proposed model enables di...
ORGANISM(S): Nomascus leucogenys Pan troglodytes Pongo pygmaeus Chlorocebus aethiops Homo sapiens 
2018-06-20 | GSE111733 | GEO
GenomicsA probabilistic framework for cellular lineage reconstruction using integrated single-cell 5-hydroxymethylcytosine and genomic DNA sequencing
A probabilistic framework for cellular lineage reconstruction using integrated single-cell 5-hydroxymethylcytosine and genomic DNA sequencing
PRJNA544412 | ENA
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