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MetabolomicsUntargeted LC-HRMS approaches combined with feature-based molecular networking to annotate reaction markers in processed foods

The rising consumption of ultra-processed foods (UPFs), linked to multiple health risks, underscores the need to characterise the chemical profile of formulated and processed goods to improve their quality and safety. This study aims to develop untargeted approaches based on LC-HRMS and LC-HRMS/M...

2025-11-12 | MTBLS12279 | MetaboLights
MetabolomicsIdentification and validation of poly-metabolite scores for diets high in ultra-processed food: An observational study and post-hoc randomized controlled crossover-feeding trial.

BACKGOUND: Ultra-processed food (UPF) accounts for a majority of calories consumed in the United States, but the impact on human health remains unclear. We aimed to identify poly-metabolite scores in blood and urine that are predictive of UPF intake.

METHODS AND FIN...

2025-07-12 | MTBLS12705 | MetaboLights
ProteomicsAllergen marker discovery and quantification
We developed a high-resolution accurate mass (HRAM)-LC-MS/MS method using the same food extract used in the ELISA method and an MS sample preparation kit. Multiple food allergen analysis was performed using 1, 5, 10, and 20 ppm of allergen-incurred processed foods. Overall, a strong correlation was ...
ORGANISM(S): Cellular Organisms 
2024-07-31 | PXD053465 | JPOST Repository
GenomicsUltra-Processed Foods drive Intestinal Barrier permeability increasing Microvascular Disease risk
Ultra-Processed Foods drive Intestinal Barrier permeability increasing Microvascular Disease risk
PRJNA596437 | ENA
TranscriptomicsUltra-Processed Foods drive Intestinal Barrier permeability increasing Microvascular Disease risk
Abstract: Our intake of ultra-processed foods has dramatically increased over the past few decades in line with the prevalence of obesity and diabetes, key risk factors for microvascular diseases such as chronic kidney disease (CKD). The extent to which long-term intake of highly processed food infl...
ORGANISM(S): Mus musculus 
2020-12-18 | GSE142261 | GEO
ProteomicsDetection of Six Commercially Processed Soy ingredients in an Incurred Food Matrix Using Parallel Reaction Monitoring
Soybean is one of the major allergenic foods in the United States, European Union, and many other countries. Soybean is commonly processed into different types of soy ingredients to achieve desired properties. The processing, however, may affect the protein profiles and protein structure, thus affec...
ORGANISM(S): Glycine Max 
2019-02-14 | PXD010843 | panorama
UnknownConsumption Patterns of Processed Foods in Singapore-A Cross-Sectional Study.
Not available
S-EPMC9498269 | biostudies-literature
UnknownUltra-Processed Foods Elicit Higher Approach Motivation Than Unprocessed and Minimally Processed Foods.
Not available
S-EPMC9253546 | biostudies-literature
UnknownUltra-Processed Foods: Definitions and Policy Issues.
Not available
S-EPMC6389637 | biostudies-literature
GenomicsUltra-processed foods sourced 7-ketositosterol aggravates colitis through gut dysbiosis induced-PDLIM3 activation
Ultra-processed foods sourced 7-ketositosterol aggravates colitis through gut dysbiosis induced-PDLIM3 activation
PRJNA1272543 | ENA
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