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MetabolomicsTo explore the role of circulating oxidized lipids in the progression and prognosis of SA-AKI by means of histochemistry

Background: Plasma oxidized lipids are intimately linked to immune regulation as bioactive mediators. However, it is not clear whether they are related to the progression of sepsis-associated acute kidney injury (SA-AKI) and the effect of continuous renal replacement therapy (CRR...

2024-12-16 | MTBLS11695 | MetaboLights
MetabolomicsUntargeted LC-HRMS Based-Plasma Metabolomics Reveals 3-O-Methyldopa as a New Biomarker of Poor Prognosis in High-Risk Neuroblastoma
Neuroblastoma (NB) is the most common extracranial malignant tumor in children. Although the survival rate of NB has improved over the years, the outcome of NB still remains poor for over 30% of cases. A more accurate risk stratification remains a key point in the study of NB and the availability of...
2023-07-14 | MTBLS4294 | MetaboLights
MetabolomicsMulti-omics Analysis of ACAD11-mediated Lipid Metabolic Reprogramming in the Prognosis of Clear Cell Renal Cell
Clear cell renal cell carcinoma (ccRCC) is pathologically characterized by profound intracellular lipid droplet accumulation. To explore the dysregulated lipid metabolic network and identify crucial drivers, an integrated transcriptomic and untargeted metabolomic analysis was conducted. In this stud...
2026-08-31 | MTBLS15414 | MetaboLights
MetabolomicsA reductionist approach using primary and metastatic cell-derived extracellular vesicles reveals hub proteins associated with oral cancer prognosis
Not available
ORGANISM(S): Homo sapiens 
ST001755 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of human CLL - a genomic approach to improve prognosis and predict therapeutic response in chronic lymphocytic leukemia - super series
This SuperSeries is composed of the following subset Series:; GSE10137: A Genomic Approach to Improve Prognosis and Predict Therapeutic Response in Chronic Lymphocytic Leukemia (Mayo_Ohio); GSE10138: A Genomic Approach to Improve Prognosis and Predict Therapeutic Response in Chronic Lymphocytic Leuk...
ORGANISM(S): Homo sapiens 
2009-11-09 | E-GEOD-10139 | biostudies-arrayexpress
TranscriptomicsSmoking Status Impacts microRNA Mediated Prognosis and Lung Adenocarcinoma Biology
Cigarette smoke is associated with the majority of lung cancers: however, 25% of lung cancer patients are non-smokers, and half of all newly diagnosed lung cancer patients are former smokers. Lung tumors exhibit distinct epidemiological, clinical, pathological, and molecular features depending on sm...
ORGANISM(S): Homo sapiens 
2014-10-30 | E-GEOD-62182 | biostudies-arrayexpress
TranscriptomicsExpression profiling of GIST: CD133 is associated with KIT exon 11 deletion, gastric location and poor prognosis
Background & Aims: In gastrointestinal stromal tumors (GIST) KIT exon 11 deletions are associated with poor prognosis. The aim of this study was to determine the gene expression profile of GIST carrying KIT exon 11 deletions and to identify genes associated with poor prognosis. Methods: Expression p...
ORGANISM(S): Homo sapiens 
2010-06-30 | E-GEOD-14755 | biostudies-arrayexpress
TranscriptomicsDynamic changes in gene expression in vivo predict prognosis of tamoxifen-treated patients with breast cancer
Tamoxifen is the most widely prescribed anti-estrogen treatment for patients with ER-positive breast cancer. However, there is still a need for biomarkers that reliably predict endocrine sensitivity in breast cancers and these may well be expressed in a dynamic manner. In this study we assessed ge...
ORGANISM(S): Homo sapiens 
2010-06-17 | E-GEOD-22386 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human chronic lymphocytic leukemia samples to improve prognosis and predict therapeutic response
Chronic lymphocytic leukemia (CLL) is a heterogeneous malignancy, characterized by a variable clinical course. While clinical and laboratory parameters are increasingly being used to refine prognosis, they do not accurately predict response to commonly used therapy. We used gene expression profilin...
ORGANISM(S): Homo sapiens 
2009-11-11 | E-GEOD-10137 | biostudies-arrayexpress
TranscriptomicsLeukemia Inhibitory Factor in C26 Cancer Cachexia
Cachexia is an exacerbating event in many types of cancer that is strongly associated with a poor prognosis. We have identified cytokine, signaling and transcription factors that are required for cachexia in the mouse C26 colon carcinoma model of cancer. C2C12 myotubes treated with conditioned mediu...
ORGANISM(S): Mus musculus 
2015-06-25 | E-GEOD-68827 | biostudies-arrayexpress
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