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MetabolomicsTranscobalamin 2 orchestrates monocyte proliferation and TLR4-driven inflammation in systemic lupus erythematosus via folate one-carbon metabolism

BACKGROUND: SLE is a complex autoimmune disease with deleterious effects on various organs. Accumulating evidence has shown abnormal vitamin B12 and one-carbon flux contribute to immune dysfunction. Transcobalamin II (TCN2) belongs to the vitamin B12-binding protein family respon...

2024-05-28 | MTBLS9136 | MetaboLights
ModelsHeldt2018 - Proliferation-quiescence decision in response to DNA damage
Heldt2018 - Proliferation-quiescence decision in response to DNA damage This model is described in the article: A comprehensive model for the proliferation-quiescence decision in response to endogenous DNA damage in human cells. ...
2024-09-02 | BIOMD0000000700 | BioModels
GenomicsMitochondria-derived nuclear ATP surge protects against mechanical confinement-induced proliferation defects
Mitochondria-derived nuclear ATP surge protects against mechanical confinement-induced proliferation defects
PRJNA1046105 | ENA
UnknownIdentification of CFAP52 as a novel diagnostic target of male infertility with defects of sperm head-tail connection and flagella development.
Not available
S-EPMC10735225 | biostudies-literature
GenomicsCystic fibrosis causes olfactory system defects by altering progenitor cell proliferation (scRNA-Seq)
Cystic fibrosis causes olfactory system defects by altering progenitor cell proliferation (scRNA-Seq)
PRJNA809339 | ENA
ProteomicsMultifunctional polyphenol-based silk hydrogel alleviates oxidative stress and enhances endogenous regeneration of osteochondral defects
The native microenvironment following osteochondral defect is not permissive for its endogenous regeneration. A variety of hydrogels have been developed to regulate cell behaviors; however, there is still a lack of hydrogels with multifunctional properties that can provide a supportive microenvironm...
ORGANISM(S): Rattus Rattus 
2021-11-28 | PXD030026 |
GenomicsCystic fibrosis causes olfactory system defects by altering progenitor cell proliferation (Bulk RNA-Seq)
Cystic fibrosis causes olfactory system defects by altering progenitor cell proliferation (Bulk RNA-Seq)
PRJNA809342 | ENA
GenomicsCystic fibrosis causes olfactory system defects by altering progenitor cell proliferation
Cystic fibrosis causes olfactory system defects by altering progenitor cell proliferation
PRJNA809332 | ENA
TranscriptomicsFunctional dissection of the Paired domain of Pax6 – distinct roles of subdomains in neurogenesis and proliferation
The transcription factor Pax6 acts as a key developmental regulator in various organs. In the developing brain Pax6 regulates patterning, neurogenesis and proliferation, but how these diverse effects are mediated at the molecular level is not well understood. As Pax6 regulates forebrain development ...
ORGANISM(S): Mus musculus 
2013-03-19 | E-GEOD-35260 | biostudies-arrayexpress
GenomicsFunctional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome
Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome
PRJNA856635 | ENA
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