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UnknownPolymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites.
Not available
S-EPMC1182139 | biostudies-literature
TranscriptomicsThe NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways
The NS1 protein of influenza virus counters host antiviral defences primarily by antagonizing the type I interferon (IFN) response. Both the N-terminal dsRNA-binding domain and the C-terminal effector domain are required for optimal suppression of host responses during infection. To better understan...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-GEOD-39200 | biostudies-arrayexpress
TranscriptomicsLethal dissemination of H5N1 influenza virus is associated with dysregulation of inflammation and lipoxin signaling in a mouse model of infection
Periodic outbreaks of highly pathogenic avian H5N1 influenza viruses and the current H1N1 pandemic highlight the need for a more detailed understanding of influenza virus pathogenesis. To investigate the host transcriptional response induced by pathogenic influenza viruses, we used a functional-geno...
ORGANISM(S): Mus musculus 
2013-07-16 | E-GEOD-48890 | biostudies-arrayexpress
UnknownImpact of Topical Interventions on the Vaginal Microbiota and Metabolome in Postmenopausal Women: A Secondary Analysis of a Randomized Clinical Trial.
Not available
S-EPMC8968546 | biostudies-literature
UnknownEarly Bacterial Coinfections in Patients Admitted to the ICU With COVID-19 or Influenza: A Retrospective Cohort Study.
Not available
S-EPMC10090795 | biostudies-literature
TranscriptomicsmicroRNA expression in human hepatitis c virus (HCV) liver biopsy samples
In order to infer the inverse expression relationships between microRNAs and mRNAs during HCV infection, we profiled both microRNA and mRNA expressions in HCV positive (HCV+) and HCV negative (HCV-) human liver biopsy tissue samples. This series includes all microRNA profiles. This series includes m...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-15288 | biostudies-arrayexpress
UnknownInduction of strain-transcending immunity against Plasmodium chabaudi adami malaria with a multiepitope DNA vaccine.
Not available
S-EPMC1087359 | biostudies-literature
TranscriptomicsThe effect of alpha, beta, gamma interferon receptors on host reponse to influenza virus in mouse embryonic fibroblasts
The objective of this study was to examine the host transcriptional response to high and low pathogenecity viruses in mouse embryonic fibroblasts (MEFs) isolated from different mouse genetic backgrounds to further understand the contribution of interferon signaling pathways to host response to influ...
ORGANISM(S): Mus musculus 
2012-04-29 | E-GEOD-37665 | biostudies-arrayexpress
TranscriptomicsAcute host transcriptonal response to r1918 influenza and r1918 influenza containing the NS1 gene from A/Texas/36/91 in A549 cells
The “Spanish influenza” of 1918 claimed an unprecedented number of lives, yet the determinants of virulence for this virus are still not fully understood. Here, we used functional genomics and an in vitro human lung epithelial cell infection model to define the global host transcriptional response t...
ORGANISM(S): Homo sapiens 
2012-05-13 | E-GEOD-37951 | biostudies-arrayexpress
UnknownEvaluation of suitable reference genes for gene expression studies in porcine PBMCs in response to LPS and LTA.
Not available
S-EPMC3584940 | biostudies-literature
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