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TranscriptomicsFurin deficiency efect on T cells
Analysis of T-cells lacking the proprotein convertase furin. Proprotein convertases promote the proteolytic maturation of proproteins. Furin is induced in activated T-cells. Results provide insight into the function of furin in T-cells. CD4+CD62L+CD44- naive, CD4+CD62L-CD44+ memory and CD4+CD25+FoxP...
ORGANISM(S): Mus musculus 
2015-08-05 | E-GEOD-67884 | biostudies-arrayexpress
ProteomicsTherapeutic anti-glioma effect of the combined action of PCSK inhibitor with the anti-tumoral factors secreted by Poly (I:C) - stimulated macrophages
Macrophages plasticity is a key feature in cancer progression. Neoplastic cells can alter their immune functions and orient them into a pro-tumoral phenotype. In this context and based on our previous work, we developed a new therapeutic strategy to switch macrophages phenotype and reactivate their ...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-23 | PXD020258 | Pride
Glioma Rat Macrophages Reactivation Proprotein convertases Poly (i:c) 
UnknownProprotein convertases: Key players in inflammation-related malignancies and metastasis.
Not available
S-EPMC7115805 | biostudies-literature
UnknownThe Proteolytic Regulation of Virus Cell Entry by Furin and Other Proprotein Convertases.
Not available
S-EPMC6784293 | biostudies-literature
GenomicsThe proprotein convertases regulate cumulus-oocyte-complex matrix integrity and cumulus cell behavior via a GDF-9 dependent mechanism
The proprotein convertases regulate cumulus-oocyte-complex matrix integrity and cumulus cell behavior via a GDF-9 dependent mechanism
PRJNA1466937 | ENA
UnknownPotent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics.
Not available
S-EPMC2834293 | biostudies-literature
UnknownCharacterization of Proprotein Convertases and Their Involvement in Virus Propagation
Not available
S-EPMC7122180 | biostudies-literature
UnknownSubstrate cleavage analysis of furin and related proprotein convertases. A comparative study.
Not available
S-EPMC2475709 | biostudies-literature
UnknownMouse Models of Human Proprotein Convertase Insufficiency.
Not available
S-EPMC8152446 | biostudies-literature
UnknownMechanism of Fine-tuning pH Sensors in Proprotein Convertases: IDENTIFICATION OF A pH-SENSING HISTIDINE PAIR IN THE PROPEPTIDE OF PROPROTEIN CONVERTASE 1/3.
Not available
S-EPMC4645620 | biostudies-literature
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