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GenomicsHDAC3 requirement for the inflammatory gene expression program in macrophages [ChIP_Seq]
Pan-Hdac inhibitors (HDACi) are endowed with a potent anti-inflammatory activity, but the relative role of each of the eleven Hdac proteins sensitive to HDACi to the inflammatory gene expression program is unknown. Using an integrated genomic approach we found that Hdac3-deficient macrophages are un...
ORGANISM(S): Mus musculus 
2012-07-08 | E-GEOD-33163 | biostudies-arrayexpress
TranscriptomicsHDAC3 requirement for the inflammatory gene expression program in macrophages [gene expression]
Pan-Hdac inhibitors (HDACi) are endowed with a potent anti-inflammatory activity, but the relative role of each of the eleven Hdac proteins sensitive to HDACi to the inflammatory gene expression program is unknown. Using an integrated genomic approach we found that Hdac3-deficient macrophages are un...
ORGANISM(S): Mus musculus 
2012-07-08 | E-GEOD-33162 | biostudies-arrayexpress
TranscriptomicsTranscription of mammalian cis-regulatory elements is restrained by actively enforced early termination [Hi-C]
Upon recruitment to active enhancers and promoters, RNA polymerase II (Pol_II) generates short non-coding transcripts of unclear function. The mechanisms that control the length and the amount of ncRNAs generated by cis-regulatory elements are largely unknown. Here, we show that the adapter protein ...
ORGANISM(S): Mus musculus 
2015-11-09 | E-GEOD-66952 | biostudies-arrayexpress
TranscriptomicsTranscription of mammalian cis-regulatory elements is restrained by actively enforced early termination [additional 4C]
Upon recruitment to active enhancers and promoters, RNA polymerase II (Pol_II) generates short non-coding transcripts of unclear function. The mechanisms that control the length and the amount of ncRNAs generated by cis-regulatory elements are largely unknown. Here, we show that the adapter protein ...
ORGANISM(S): Mus musculus 
2015-11-09 | E-GEOD-72958 | biostudies-arrayexpress
TranscriptomicsTranscription of mammalian cis-regulatory elements is restrained by actively enforced early termination [4C]
Upon recruitment to active enhancers and promoters, RNA polymerase II (Pol_II) generates short non-coding transcripts of unclear function. The mechanisms that control the length and the amount of ncRNAs generated by cis-regulatory elements are largely unknown. Here, we show that the adapter protein ...
ORGANISM(S): Mus musculus 
2015-11-09 | E-GEOD-66950 | biostudies-arrayexpress
TranscriptomicsTranscription of mammalian cis-regulatory elements is restrained by actively enforced early termination [additional RNA]
Upon recruitment to active enhancers and promoters, RNA polymerase II (Pol_II) generates short non-coding transcripts of unclear function. The mechanisms that control the length and the amount of ncRNAs generated by cis-regulatory elements are largely unknown. Here, we show that the adapter protein ...
ORGANISM(S): Mus musculus 
2015-11-09 | E-GEOD-73021 | biostudies-arrayexpress
GenomicsTranscription of mammalian cis-regulatory elements is restrained by actively enforced early termination [ChIP-Seq]
Upon recruitment to active enhancers and promoters, RNA polymerase II (Pol_II) generates short non-coding transcripts of unclear function. The mechanisms that control the length and the amount of ncRNAs generated by cis-regulatory elements are largely unknown. Here, we show that the adapter protein ...
ORGANISM(S): Mus musculus 
2015-11-09 | E-GEOD-66951 | biostudies-arrayexpress
TranscriptomicsTranscription of mammalian cis-regulatory elements is restrained by actively enforced early termination [RNA]
Upon recruitment to active enhancers and promoters, RNA polymerase II (Pol_II) generates short non-coding transcripts of unclear function. The mechanisms that control the length and the amount of ncRNAs generated by cis-regulatory elements are largely unknown. Here, we show that the adapter protein ...
ORGANISM(S): Mus musculus 
2015-11-09 | E-GEOD-66953 | biostudies-arrayexpress
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