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MetabolomicsExercise-associated metabolomic changes in mouse prostate tumors
This study investigated exercise-associated metabolic alterations in prostate tumor tissues from Pb-Cre; Pten (fl/fl) mice. LC-MS-based metabolomic profiling was performed to compare prostate tumor tissues from control and voluntary exercise groups.
2026-05-23 | MTBLS14566 | MetaboLights
MetabolomicsHigh-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program
Systemic metabolic alterations associated with increased consumption of saturated fat and obesity are linked with increased risk of prostate cancer progression and mortality, but the molecular underpinnings of this association are poorly understood. Here, we demonstrate in a murine prostate cancer m...
2019-08-22 | MTBLS135 | MetaboLights
MetabolomicsMetabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival

The spread of cancer to bone is invariably fatal, with complex cross-talk between tumor cells and the bone microenvironment responsible for driving disease progression. By combining in silico analysis of patient datasets with metabolomic profiling of prostate cancer cells cultured with bone cells...

2024-08-19 | MTBLS3973 | MetaboLights
MetabolomicsPeak Learning of Mass Spectrometry Imaging Data Using Artificial Neural Networks (Prostate tissue)
Not available
ORGANISM(S): Homo sapiens;Mus musculus 
ST001857 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of normal, tumor and pure stromal tissue samples from patients with prostate adenocarcinoma, together with 4 cell lines
We have used normal, tumoral and pure stromal whole tissue samples, and cells lines in order to identify new markers of prostate cancer.
The normal, tumoral and stromal tissue were obtained from patients diagnosed with prostate adenocarcinoma.
ORGANISM(S): Homo sapiens 
2008-11-12 | E-MEXP-1331 | biostudies-arrayexpress
TranscriptomicsLineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell of origin model for prostate cancer heterogeneity
We used RNA-seq to compare the expression profiles of mouse prostate tumors originated from epithelial basal cells to those originated from luminal cells. We next generated expression signatures for both basal and luminal origin tumors by comparison of tumor samples to their respective controls. By ...
ORGANISM(S): Mus musculus 
2013-01-14 | E-GEOD-39509 | biostudies-arrayexpress
TranscriptomicsGene-expression profiling of prostate tumors
Increasing evidence suggests that prostate cancer is overdiagnosed and overtreated, and prognostic biomarkers would aid in treatment selection. To define prognostic biomarkers for aggressive prostate cancer, we carried out gene-expression profiling of 98 prostate tumors and 52 benign adjacent prosta...
ORGANISM(S): Homo sapiens 
2012-08-23 | E-GEOD-40272 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human prostate tissues obtained from multiple Institutions
Microarray studies of Prostate tissues obtained from multiple Institutions. Analysis done during Aug. 2002 to June 2004.
ORGANISM(S): Homo sapiens 
2006-06-16 | E-TABM-26 | biostudies-arrayexpress
ProteomicsSpatiotemporal proteomics of hormone treated mice (urine across time, prostate tissue)
Benign prostatic hyperplasia and related lower urinary tract symptoms remain common, costly, and impactful issues for aging males. Etiology and pathogenesis are multifactorial and include steroid hormone changes and inflammation. Noninvasive markers could one day inform personalized medicine, but in...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD014416 | Pride
Mus musculus Urine Proteomics Hormone Prostate 
TranscriptomicsGene expression in benign and prostate cancer tissue
Benign prostate tissue and prostate cancer tissue (untreated, androgen deprivation therapy responding, or castrate-resistant) was collected from patients at the time of transurethral resection of the prostate surgery. 24 samples, technical replicates.
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-28680 | biostudies-arrayexpress
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