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MetabolomicsMolecular characterization of firefly nuptial gifts: a multi-omics approach sheds light on postcopulatory sexual selection
Postcopulatory sexual selection is recognized as a key driver of reproductive trait evolution, including the machinery required to produce endogenous nuptial gifts. Despite the importance of such gifts, the molecular composition of the non-gametic components of male ejaculates and their interactions...
2016-12-22 | MTBLS362 | MetaboLights
ProteomicsCharacterization of WN NS3 and AspN proteases
Characterization of WN NS3 protease and characterization of AspN protease with double digestion protocol
ORGANISM(S): Homo sapiens (Human) 
2021-02-04 | PXD022973 | Pride
Htps Protease characterization 
MetabolomicsCharacterization of active peptides derived from three leeches and comparison of their anti-thrombotic mechanisms using the tail vein thrombosis model in mice and metabonomics

BACKGROUND AND AIMS: The increasing incidence of cardiovascular diseases has created an urgent need for safe and effective anti-thrombotic agents. Leech, as a traditional Chinese medicine, has the effect of promoting blood circulation and removing blood stasis, but its real mater...

2024-01-18 | MTBLS9306 | MetaboLights
TranscriptomicsReaeration timecourse from a defined hypoxia model
Reaeration timecourse from a defined hypoxia model in Mycobacterium tuberculosis. The mechanism by which mycobacteria return to a replicating state upon re-exposure to favorable conditions is not well understood. In this study, we utilized reaeration from a defined hypoxia model to characterize the...
ORGANISM(S): Mycobacterium tuberculosis 
2010-07-28 | E-GEOD-21590 | biostudies-arrayexpress
ProteomicsD. magna CT448 protease specificity
Mass developments of toxin-producing cyanobacteria are frequently observed in freshwater ecosystems due to eutrophication and global warming. These mass developments can partly be attributed to cyanobacterial toxins, such as protease inhibitors (PIs), which inhibit digestive serine proteases of Daph...
ORGANISM(S): Daphnia magna 
2018-10-04 | PXD010978 | Pride
Ct448 pics protease specificity 
ProteomicsAtLEGbeta / gamma protease specificity characterization by PICS
Arabidopsis thaliana Legumain (aka VPE) beta / gamma proteases were characterized for their cleavage specificity by PICS (Proteomic Identification of protease Cleavage Sites).
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Escherichia coli 
2020-07-29 | PXD019220 | Pride
Arabidopsis legumain beta gamma protease 
ProteomicsPrkA regulates Bacillus subtilis sporulation through a Lon protease activity
In Bacillus subtilis, sporulation is a sequential and highly regulated process. Phosphorylation events by Histidine or Serine/Threonine kinases are key points in this regulation. PrkA has been proposed to be an essential Serine kinase for the initiation of sporulation but its kinase activity has not...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2022-10-15 | PXD032931 | Pride
Atpase Prka Lon protease Sporulation Phosphorylation Bacillus subtilis 
ProteomicsMolecular characterization of Histomonas meleagridis exoproteome with emphasis on protease secretion and parasite-bacteria interaction
Exoproteome from parasitic protists constitutes of extracellular proteins which play a fundamental role in multifactorial host-parasite interactions. Lytic factors, especially secreted proteases in extracellular milieu, are capable to modulate tissue invasion, thereby aggravating host susceptibility...
ORGANISM(S): Histomonas meleagridis 
2019-02-11 | PXD012037 | Pride
Histomonas meleagridis  exoproteome profiling  protein secretion  shotgun exoproteomics  proteases  protease inhibitor  protozoa  microbial microenvironment  pathogenesis  virulence factors 
ProteomicsCharacterization of MdpS: An In-depth Analysis of a MUC5B-Degrading Protease from Streptococcus oralis
Oral biofilms, comprising hundreds of bacteria and other microorganisms on oral mucosal and dental surfaces, play a central role in oral health and disease dynamics. Streptococcus oralis, a key constituent of these biofilms, contribute significantly to their formation, serving as an early colonizer ...
ORGANISM(S): Homo sapiens (Human) 
2024-04-18 | PXD046810 | Pride
Serine protease O-glycosylation Mucin degradation Oral biofilm Muc5b Streptococcus oralis 
ProteomicsMolecular characterization of Histomonas meleagridis exoproteome with emphasis on protease secretion and parasite-bacteria interaction - SWATH dataset
Exoproteome from parasitic protists constitutes of extracellular proteins which play a fundamental role in multifactorial host-parasite interactions. Lytic factors, especially secreted proteases in extracellular milieu, are capable to modulate tissue invasion, thereby aggravating host susceptibility...
ORGANISM(S): Histomonas meleagridis 
2019-02-11 | PXD012038 | Pride
Histomonas meleagridis  exoproteome profiling  protein secretion  shotgun exoproteomics  proteases  protease inhibitor  protozoa  microbial microenvironment  pathogenesis  virulence factors 
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