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ProteomicsThromboxane-A Synthase 1 as a Potential Dual Biomarker for Metastatic Prostate Cancer and Atherosclerosis: Insights from a Nanomedicine Protein Corona, Machine Learning, and Actual Causality Approaches
Prostate cancer (PC) is the most common cancer among men in the United States, while atherosclerosis (ASCVD) is the most prevalent cardiovascular disease (CVD) associated with it. CVD, particularly ASCVD, has been shown to contribute to metastatic prostate cancer (mPC) progression. Identifying blood...
ORGANISM(S): Homo sapiens (Human) 
2025-11-21 | PXD057863 | Pride
Protein corona Bottom up proteomics Machin learning Human plasma 
ProteomicsIsomeric Differences in Nanoparticle’s Surface Chemistry Alters Macrophage Interactions In Vitro Due to Protein Corona
The interactions of nanoparticles (NPs) with macrophages after intravenous injection are critical in determining their biodistribution and pharmacokinetics. The formation of protein corona (PC) on the nanoparticles, often a result of NP-plasma protein interactions, influences macrophage response, th...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD051722 | Pride
Protein corona 
ProteomicsNanoparticle protein corona LC-MS/MS
Engineered nanoparticles for biomedical applications require increased effectiveness in targeting specific cells while preserving non-target cells’ safety. Native nanoparticles entering a protein-rich liquid media quickly form a macromolecular structure called protein corona. This protein structure...
ORGANISM(S): Bos taurus (Bovine) 
2017-02-28 | PXD004636 | Pride
Protein corona (pc) Nanoparticle (np) Lc-ms/ms 
ProteomicsCombining confocal microscopy, dSTORM, and mass spectroscopy to unveil the evolution of the protein corona associated with nanostructured lipid nanocarriers during blood-brain barrier crossing
Upon entering in contact with the biological environment, nanostructures are immediately covered by biomolecules, and in particular proteins forming the so-called “protein corona” (PC). The phenomenon of PC formation has gained great attention in recent years due to its implication for the use of na...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-14 | PXD031034 | Pride
Protein corona  blood-brain barrier  lipid nanoparticles  magnetic nanoparticles  super resolution microscopy  dstorm  mass spectroscopy. 
UnknownSilver nanoparticle protein corona composition in cell culture media.
Not available
S-EPMC3767594 | biostudies-literature
UnknownComparison of nanotube-protein corona composition in cell culture media.
Not available
S-EPMC3725593 | biostudies-literature
ProteomicsDetection of Circulating Serum Protein Biomarkers of Non-muscle Invasive Bladder Cancer after the Protein Corona-Silver Nanoparticles Analysis by SWATH-MS
Because cystoscopy is expensive and invasive, a new method of detecting non-invasive muscular bladder cancer (NMIBC) is needed. This study aims to identify potential serum protein markers for NMIBC to improve diagnosis and to found treatment approaches to avoid disease progression to a life-threaten...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD028310 | Pride
Protein corona (pc)  silver nanoparticles (agnps)  bladder cancer (bc)  bi-omarkers  fingerprinting  swath-ms 
UnknownFormation of a protein corona on silver nanoparticles mediates cellular toxicity via scavenger receptors.
Not available
S-EPMC4274384 | biostudies-literature
UnknownIsomeric Differences in Nanoparticle's Surface Chemistry Alter Macrophage Interactions In Vitro Due to Protein Corona.
Not available
S-EPMC12461424 | biostudies-literature
UnknownQuantitative comparison of the protein corona of nanoparticles with different matrices.
Not available
S-EPMC9594119 | biostudies-literature
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