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Protein disulfide isomerases (PDIs) aid protein folding and assembly by catalyzing formation and shuffling of cysteine disulfide bonds in the endoplasmic reticulum (ER). Many members of the PDI family are expressed in mammals but the roles of specific PDIs in vivo are poorly understood. A recent hom...
ORGANISM(S): Mus musculus 
Treatment of Neuroblastoma Cells with Inhibitors of Protein Disulfide Isomerase Upregulates NQO1 Activity
Dual roles for a tick protein disulfide isomerase during the life cycle of the Lyme disease agent
Expression data from SH-SY5Y neuroblastoma cells treated with the protein disulfide isomerase inhibitor origamicin
Dual roles for a tick protein disulfide isomerase during the life cycle of the Lyme disease agent [I. scapularis]
Metabolic reprogramming is a ubiquitous feature of transformed cells, comprising one of the hallmarks of cancer and enabling neoplastic cells to adapt to new environments. Accumulated evidence reports on the failure of some neoplastic cells to convert mannose-6-phosphate into fructose-6-phosphate, t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-02-16 | MSV000094098 | MassIVE
Therapeutic Targeting of Protein Disulfide Isomerase PDIA1 in Multiple Myeloma
Identification of transcripts induced after treatment with protein disulfide isomerase inhibitor E64FC65 and panobinostat in PANC-1 cells
To understand the immunomodulation roles of Ixodes scapularis protein disulfide isomerase A6 (IsPDIA6), we utilized RNA sequencing (RNA-seq) to investigate the effect of IsPDIA6 on the murine transcriptome.
ORGANISM(S): Mus musculus 
2024-10-14 | GSE273486 | GEO
Bioinformatic analysis of Protein Disulfide Isomerase A1 (PDIA1)-associated pathways towards developing stratified breast cancer therapies
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