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MetabolomicsSerum protein N-glycosylation changes in multiple myeloma

BACKGROUND: Multiple myeloma is characterized by clonal proliferation of malignant plasma cells in the bone marrow that produce monoclonal immunoglobulins. N-glycosylation changes of these monoclonal immunoglobulins have been reported in multiple myeloma, but previous studies on...

2022-04-27 | MTBLS676 | MetaboLights
MetabolomicsThe Bardet-Biedl protein Bbs1 controls photoreceptor outer segment protein and lipid composition

Summary

Primary cilia are key sensory organelles whose dysfunction leads to ciliopathy disorders such as Bardet-Biedl syndrome (BBS). Retinal degeneration is common in ciliopathies, since the outer segments (OSs) of photoreceptors are highly specialized primary cilia. BBS...

2022-02-18 | MTBLS4013 | MetaboLights
MetabolomicsIntegrative of Single-Cell RNA Sequencing and Metabolomics Decipher the Imbalanced Lipid-Metabolism in Maladaptive Immune Responses during Sepsis
To identify differentially expressed lipid metabolism-related genes (DE-LMRGs) responsible for immune dysfunction in sepsis. Machine learning algorithms were applied for screening hubgenes related to lipid metabolism. CIBERSORT and Single-sample GSEA were employed for assessing the immune cell infil...
2024-09-26 | MTBLS7315 | MetaboLights
MetabolomicsNon-targeted metabolomics sequencing of Lactobacillus salivarius fermentation broth
To conduct an in-depth analysis of which metabolites in the antiviral-effective lactic acid bacteria supernatant are playing a role, a pretreatment approach was selected. Non-targeted metabolomic analysis was performed on the differential metabolites between LSD2339-CFS and LSM231-CFS, which exhibit...
2026-06-08 | MTBLS14704 | MetaboLights
MetabolomicsMetabolome sequencing data of Hu Lambs

Fecal metabolomic data of Hu sheep collected before and after weaning at 30, 40, and 50 days of age under three weaning strategies: abrupt weaning , single intermittent separation, and two-stage intermittent separation .

2026-03-28 | MTBLS14172 | MetaboLights
MetabolomicsMetabolome sequencing data of Hu Lambs

Serum metabolomic data of Hu sheep collected before and after weaning at 30, 40, and 50 days of age under three weaning strategies: abrupt weaning, single intermittent separation, and two-stage intermittent separation.

2026-03-28 | MTBLS14174 | MetaboLights
MetabolomicsMetabolomics analysis was used to resolve metabolites affecting the protein oil content of soybean.
Soybean (Glycine max (L.)) originated in China more than 5000 years ago, and the country is currently the third largest producer of soybeans in the world (Hymowitz et al., 2015). Based on a wild soybean Chromosome Segment Substitution Line (CSSL) population were constructed by crossing with the cult...
2024-11-13 | MTBLS9424 | MetaboLights
MetabolomicsNutritional quality and genetic differences of five amaranth cultivars revealed by metabolome profiling and whole-genome sequencing (Seed assays)

BACKGROUND: Amaranth (Amaranthus spp.) has high nutritional quality, with edible grain and leaves, and many agronomic advantages, making it a promising part of the solution for global food insecurity. However, we lack comprehensive metabolomic and genome sequence data fo...

2025-02-25 | MTBLS815 | MetaboLights
MetabolomicsNutritional quality and genetic differences of five amaranth cultivars revealed by metabolome profiling and whole-genome sequencing (Leaf assays)

BACKGROUND: Amaranth (Amaranthus spp.) has high nutritional quality, with edible grain and leaves, and many agronomic advantages, making it a promising part of the solution for global food insecurity. However, we lack comprehensive metabolomic and genome sequence data fo...

2025-02-25 | MTBLS3498 | MetaboLights
MetabolomicsDysbiosis of Gut Microbiota and Metabolomic Alterations in Myasthenia Gravis: Insights from 16S rRNA Sequencing and Untargeted Metabolomics

Background: Myasthenia gravis (MG) is an autoimmune disorder of neuromuscular transmission. Gut dysbiosis has been implicated in autoimmune pathogenesis, yet integrated microbial and metabolomic profiling in MG remains scarce.

Objectives:  To characterize gut microbiota and t...

2026-04-13 | MTBLS14266 | MetaboLights
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