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TranscriptomicsTranscriptional profiling of mouse glomerulus in lipopolysaccharide-induced proteinuria model
The pathogenic mechanisms of common kidney glomerular diseases, including the vast majority of cases of proteinuria, remain unknown. To gain insight into the pathogenesis of proteinuria development, we characterized the glomerular gene expression changes that accompany early stages of proteinuria in...
ORGANISM(S): Mus musculus 
2009-08-25 | E-GEOD-12599 | biostudies-arrayexpress
TranscriptomicsExpression data from female rat kidney: pathophysiology of proteinuria
This study was designed to investigate gene expression in kidneys of adult female Sabra rats (SBH/y and SBN/y rat strains) with two indwelling kidneys or after uni-ninephrectomy, seeking those genes that are differentially expressed between the two strains, and between animals with one or two kidney...
ORGANISM(S): Rattus norvegicus 
2009-01-31 | E-GEOD-14666 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of decidua basalis from women with normal pregnancies or preeclampsia and/or fetal growth restriction
The aim of the study was to compare gene expression profiles in decidua basalis from cases with complicated pregnancies to those from healthy pregnant controls. Cases included pregnant women with preeclampsia (PE) and/or fetal growth restriction (FGR). Decidual tissue was obtained by vacuum suction ...
ORGANISM(S): Homo sapiens 
2007-08-31 | E-MEXP-1050 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat Dahl salt-sensitive strain development of proteinuria
To get more insight in cause and consequences of proteinuria, we studied glomerular gene expression patterns before and after the onset of increased urinary albumin excretion in a proteinuric rat strain. Spontaneously proteinuric Dahl salt-sensitive rats (Dahl SS) were compared to non-proteinuric, s...
ORGANISM(S): Rattus norvegicus 
2009-01-14 | E-GEOD-13810 | biostudies-arrayexpress
GenomicsSpatiotemporal landscape of kidney tubular responses to glomerular proteinuria
Spatiotemporal landscape of kidney tubular responses to glomerular proteinuria
PRJNA903394 | ENA
ProteomicsMolecular Signatures of Preeclampsia and Gestational Diabetes Mellitus Utilizing Multi-Omics Analyses, Part 1
The application of multi-omic evaluations, multi-dimensional analysis methods, and new cheminformatics-based visualization tools to provide an in depth understanding of the molecular changes taking place in preeclampsia (PRE) and gestational diabetes mellitus (GDM) patients. Since PRE and GDM are tw...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-01 | MSV000085357 | MassIVE
ProteomicsMolecular Signatures of Preeclampsia and Gestational Diabetes Mellitus Utilizing Multi-Omics Analyses, Part 2
The application of multi-omic evaluations, multi-dimensional analysis methods, and new cheminformatics-based visualization tools to provide an in depth understanding of the molecular changes taking place in preeclampsia (PRE) and gestational diabetes mellitus (GDM) patients. Since PRE and GDM are tw...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-02 | MSV000085361 | MassIVE
TranscriptomicsTranscriptional profiling of mouse glomerulus in lipopolysaccharide-induced proteinuria model
The pathogenic mechanisms of common kidney glomerular diseases, including the vast majority of cases of proteinuria, remain unknown. To gain insight into the pathogenesis of proteinuria development, we characterized the glomerular gene expression changes that accompany early stages of proteinuria in...
ORGANISM(S): Mus musculus 
2009-08-26 | GSE12599 | GEO
TranscriptomicsExpression data from rat kidney: pathophysiology of proteinuria
This SuperSeries is composed of the following subset Series: GSE14666: Expression data from female rat kidney: pathophysiology of proteinuria GSE14676: Expression data from male rat kidney: pathophysiology of proteinuria Refer to individual Series
ORGANISM(S): Rattus norvegicus 
2009-02-03 | E-GEOD-14677 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human adipose tissue, decidua and placenta from patients with preeclampsia vs. unaffected indviduals reveals dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia
Preeclampsia complicates more than 3% of all pregnancies in the United States and Europe. High-risk populations include women with diabetes, dyslipidemia, thrombotic disorders, hyperhomocysteinemia, hypertension, renal diseases, previous preeclampsia, twin pregnancies, and low socioeconomic status. ...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6573 | biostudies-arrayexpress
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