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MetabolomicsThermal Profiling Maps Multilayered Organization of the Mitochondrial Proteome

Mitochondria execute essential metabolic, biosynthetic, and signaling functions, yet the regulatory principles governing their proteome remain incompletely understood. Here, we develop a thermal proteome profiling (TPP) workflow applied directly to purified mitochondria, enabling systematic analy...

2025-12-08 | MTBLS7386 | MetaboLights
MetabolomicsCTH exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation
Macrophages play a crucial role in the inflammatory response to the human stomach pathogen Helicobacter pylori, which infects half of the world's population and causes gastric cancer. Recent studies have highlighted the importance of macrophage immunometabolism in their activation state and function...
2022-06-14 | MTBLS2851 | MetaboLights
GenomicsCell size-dependent mRNA transcription drives proteome remodeling [RNA-seq]
Cell size-dependent mRNA transcription drives proteome remodeling [RNA-seq]
PRJNA1443297 | ENA
GenomicsCell size-dependent mRNA transcription drives proteome remodeling [SLAM-seq]
Cell size-dependent mRNA transcription drives proteome remodeling [SLAM-seq]
PRJNA1441515 | ENA
GenomicsGlobal organelle profiling reveals subcellular localization and remodeling at proteome scale
Global organelle profiling reveals subcellular localization and remodeling at proteome scale
PRJNA1165290 | ENA
MetabolomicsMMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis

Ferroptosis is a form of regulated cell death with roles in degenerative diseases and cancer. Excessive iron-catalyzed peroxidation of membrane phospholipids, especially those containing the polyunsaturated fatty acid arachidonic acid (AA), is central in driving ferroptosis. Here, we reveal that ...

2023-09-06 | MTBLS8280 | MetaboLights
UnknownProteome Dynamics Reveals Pro-Inflammatory Remodeling of Plasma Proteome in a Mouse Model of NAFLD.
Not available
S-EPMC5310220 | biostudies-literature
ProteomicsInfluenza virus infection leads to global cardiac proteome remodeling during convalescence
Influenza virus infection leads to global cardiac proteome remodeling during convalescence MTD project_description "Influenza virus infections lead to more than 500,000 hospitalizations in the U.S. every year. Patients with cardiovascular diseases have been shown to be at high risk of influenza medi...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-01 | PXD015992 | Pride
Influenza virus  proteome  remodeling  convalescence  heart 
GenomicsAzacitidine treated AML cells reveals highly variable cell surface proteome remodeling [Illumina]
Azacitidine treated AML cells reveals highly variable cell surface proteome remodeling [Illumina]
PRJNA507643 | ENA
GenomicsAzacitidine treated AML cells reveals highly variable cell surface proteome remodeling [Affymetrix]
Azacitidine treated AML cells reveals highly variable cell surface proteome remodeling [Affymetrix]
PRJNA507808 | ENA
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