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MetabolomicsMetabolomic and Proteomic Stratification of Equine Osteoarthritis

Osteoarthritis (OA) is characterised by loss of articular cartilage, synovial membrane dysfunction and subchondral sclerosis. Few studies have used a global approach to stratify equine synovial fluid (SF) molecular profiles according to OA severity. SF was collected from 58 metacarpophalangeal (M...

2025-10-16 | MTBLS1645 | MetaboLights
MetabolomicsHaplotype-resolved female and male genomes reveal sex-specific genomic regions and provide insights into thermal stress in Scapharca subcrenata

Integrated analyses of transcriptomic, proteomic and metabolomic data sets consistently highlights the crucial involvement of protein function and retinol metabolism pathways in the heat-resistant strain of S. subcrenata. These findings underscore the significance of these pathways in e...

2024-11-11 | MTBLS11038 | MetaboLights
ProteomicsChild murder in the Early Bronze Age: proteomic sex identification of a cold case from Schleinbach, Austria
The identification of sex-specific peptides in human tooth enamel by nanoflow liquid chromatography-tandem mass spectrometry (nanoLC-MS/MS) represents a quantum leap for the study of childhood and social relations more generally. Determining sex-related differences in prehistoric child rearing and m...
ORGANISM(S): Homo sapiens (Human) 
2021-06-01 | PXD018069 | Pride
Impression fractures Infanticide Peptides Proteomic sex identification Bronze age Otitis 
UnknownIdentification of Disease-Relevant, Sex-Based Proteomic Differences in iPSC-Derived Vascular Smooth Muscle Cells.
Not available
S-EPMC11719605 | biostudies-literature
TranscriptomicsIntegrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression
Sexual differentiation of malaria parasites into gametocytes in the vertebrate host and subsequent gamete fertilisation in mosquitoes is essential for the spreading of the disease. The molecular processes orchestrating these transitions are far from fully understood. Here we report the first transcr...
ORGANISM(S): Plasmodium falciparum 
2016-06-28 | E-GEOD-75795 | biostudies-arrayexpress
ProteomicsIdentification of Disease-relevant, Sex-based Proteomic Differences in iPSC-derived Vascular Smooth Muscle
The prevalence of cardiovascular disease varies with sex, and the impact of intrinsic sex-based differences on vasculature is not well understood. Animal models can provide important insight into some aspects of human biology, however not all discoveries in animal systems translate well to humans. T...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-07-23 | MSV000095417 | MassIVE
ProteomicsPart I: Proteomics Target Approach for Taxonomic and Sex Identification in Modern and Archaeological Enamel Caprines
. In this study, we applied proteomic analytical methods to modern caprine (sheep, Ovis aries and goat, Capra hircus) tooth enamel to establish a reliable method for identifying species-specific and sex-specific peptides. Utilizing single amino acid variations (SAAVs) in Enamelin (Enam) and Amelogen...
ORGANISM(S): Capra hircus (Goat) 
2025-09-15 | PXD058275 | Pride
Species Amel Caprines Sex Enam 
ProteomicsGendered burial practices of early Bronze Age children align with peptide-based sex identification: a case study from Franzhausen I, Austria
Gendered burial practices that differentiate between men and women by the way the body was placed were used over large parts of Central Europe in the Late Neolithic and Early Bronze Age (c. 2900−1600 BC). The differentiation of bodies placed on the left/right side in opposite orientation was extende...
ORGANISM(S): Homo sapiens (Human) 
2022-06-24 | PXD026419 | Pride
Bronze age Sex Enamel peptides Gender Burial practice 
UnknownChild murder in the Early Bronze Age: proteomic sex identification of a cold case from Schleinbach, Austria.
Not available
S-EPMC7584537 | biostudies-literature
ProteomicsSILAC-Based Proteomics of Primary Human Kidney Cells treated with Sex Hormones.
Male sex predispose to many kidney diseases. Considering that androgens exert deleterious effects in a variety of cell types within kidney, we hypothesized that dihydrotestosterone (DHT) would impair the biology of the renal tubular cell by inducing changes in the proteome. We employed stable isotop...
ORGANISM(S): Homo sapiens (Human) 
2017-01-17 | PXD003811 | Pride
Sex hormones Silac Kidney cells Proteomics 
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